Ovarian stimulation protocols for IVF: is more better than less?, Reproductive BioMedicine Online, vol.34, pp.345-353, 2017. ,
Screening for abnormalities of chromosomes X, Y, and 18 and for diploidy in spermatozoa from infertile men participating in an in vitro fertilization-intracytoplasmic sperm injection program, Fertility and Sterility, vol.72, pp.696-701, 1999. ,
Preimplantation genetic screening reveals a high incidence of aneuploidy and mosaicism in embryos from young women undergoing IVF, Hum Reprod, vol.21, pp.223-233, 2006. ,
Milder ovarian stimulation for in-vitro fertilization reduces aneuploidy in the human preimplantation embryo: a randomized controlled trial, Human Reproduction, vol.22, pp.980-988, 2007. ,
Morphological and cytogenetic analysis of human giant oocytes and giant embryos, Hum Reprod, vol.17, pp.2394-2401, 2002. ,
Detection of DNA fragmentation and meiotic segregation in human with isolated teratozoospermia, J Assist Reprod Genet, vol.28, pp.41-48, 2011. ,
Chromosome analysis of epididymal and testicular spermatozoa in patients with azoospermia, Eur J Hum Genet, vol.10, pp.362-366, 2002. ,
Sperm aneuploidy in infertile men, Reproductive BioMedicine Online, vol.6, pp.310-317, 2003. ,
Aneuploidy rate in spermatozoa of selected men with abnormal semen parameters, Hum Reprod, vol.16, pp.1172-1179, 2001. ,
Abnormally fertilized oocytes can result in healthy live births: improved genetic technologies for preimplantation genetic testing can be used to rescue viable embryos in in vitro fertilization cycles, Fertility and Sterility, vol.108, pp.1007-1015, 2017. ,
Aneuploid analysis of tripronuclear zygotes derived from in vitro fertilization and intracytoplasmic sperm injection in humans, Fertil Steril, vol.83, pp.1845-1848, 2005. ,
Age-Related Loss of Cohesion: Causes and Effects, Int J Mol Sci, vol.18, p.1578, 2017. ,
Evidence that weakened centromere cohesion is a leading cause of age-related aneuploidy in oocytes, Curr Biol, vol.20, pp.1522-1528, 2010. ,
Impact of Maternal Age on Oocyte and Embryo Competence, Front Endocrinol (Lausanne), vol.9, p.327, 2018. ,
Restarting life: fertilization and the transition from meiosis to mitosis, Nat Rev Mol Cell Biol, vol.14, pp.549-562, 2013. ,
Paternal factors contributing to embryo quality, J Assist Reprod Genet, vol.35, pp.1953-1968, 2018. ,
Increased Incidence of Meiotic Anomalies in Oligoasthenozoospermic Males Preselected for Intracytoplasmic Sperm Injection, J Assist Reprod Genet, vol.17, pp.307-309, 2000. ,
Oocyte ageing and its cellular basis, Int J Dev Biol, vol.56, pp.841-852, 2013. ,
Fertilization abnormalities following human in vitro fertilization and intracytoplasmic sperm injection, Microsc Res Tech, vol.61, pp.358-361, 2003. ,
Sperm DNA Fragmentation is Significantly Increased in Those Men with Morphologically Abnormal Spermatozoa, JFIV Reprod Med Genet, vol.02, p.3, 2014. ,
High Levels of DNA Fragmentation Observed in an Infertile Population Attending a Fertility Center are Related to Advanced Paternal Age. ResearchGate, 2012. ,
High Aneuploidy Rates Observed in Embryos Derived from Donated Oocytes are Related to Male Aging and High Percentages of Sperm DNA Fragmentation, Clin Med Insights Reprod Health, vol.9, pp.21-27, 2015. ,
Sperm DNA fragmentation index does not correlate with blastocyst aneuploidy or morphological grading, PLoS One, vol.12, p.179002, 2017. ,
Fertilization abnormalities and pronucleus size asynchrony after intracytoplasmic sperm injection are related to oocyte postmaturity, Fertility and Sterility, vol.72, pp.245-252, 1999. ,
Self-correction in tripronucleated human embryos, Fertil Steril, vol.96, pp.951-956, 2011. ,
Origin of tripronucleate zygotes after intracytoplasmic sperm injection, Hum Reprod, vol.12, pp.2762-2765, 1997. ,
A high oocyte yield for intracytoplasmic sperm injection treatment is associated with an increased chromosome error rate, Fertility and Sterility, vol.91, pp.733-738, 2009. ,
Meiosis and maternal aging: insights from aneuploid oocytes and trisomy births, Cold Spring Harb Perspect Biol, vol.7, p.17970, 2015. ,
Egg maturity assessment prior to ICSI prevents premature fertilization of late-maturing oocytes, J Assist Reprod Genet, vol.36, pp.445-452, 2019. ,
Impact of oocyte preincubation time on fertilization, embryo quality and pregnancy rate after intracytoplasmic sperm injection, Reproductive BioMedicine Online, vol.8, pp.682-686, 2004. ,
The effect of insemination/injection time on the results of IVF and ICSI, Hum Reprod, vol.16, pp.1708-1713, 2001. ,
Age-related aneuploidy through cohesion exhaustion, EMBO Rep, vol.13, pp.539-546, 2012. ,
Impact of sperm genome decay on Day-3 embryo chromosomal abnormalities from advancedmaternal-age patients, Molecular Reproduction and Development, vol.82, pp.809-819, 2015. ,
Diagnosis of abnormal human fertilization status based on pronuclear origin and/or centrosome number, J Assist Reprod Genet, vol.32, pp.1589-1595, 2015. ,
Telomeres and human reproduction, Fertil Steril, vol.99, pp.23-29, 2013. ,
Telomeres and meiosis in health and disease, Cell Mol Life Sci, vol.64, pp.115-116, 2007. ,
Male and female genomes associated in a single pronucleus in human zygotes, Biol Reprod, vol.52, pp.653-657, 1995. ,
The chromosomal complements of multipronuclear human zygotes resulting from intracytoplasmic sperm injection, Hum Reprod, vol.11, pp.2496-2501, 1996. ,
Paternal contribution to aneuploidy in preimplantation embryos, Reproductive BioMedicine Online, vol.18, pp.536-542, 2009. ,
Embryonic development after microsurgical repair of polyspermic human zygotes, Fertility and Sterility, vol.52, pp.373-380, 1989. ,
In vitro development and chromosome constitution of embryos derived from monopronucleated zygotes after intracytoplasmic sperm injection, Fertil Steril, vol.99, pp.897-902, 2013. ,
Effect of the male factor on the clinical outcome of intracytoplasmic sperm injection combined with preimplantation aneuploidy testing: observational longitudinal cohort study of 1,219 consecutive cycles, Fertility and Sterility, vol.108, pp.961-972, 2017. ,
Chromosome abnormalities in human embryos, Hum Reprod Update, vol.4, pp.842-855, 1998. ,
Origin of single pronucleated human zygotes, J Assist Reprod Genet, vol.10, pp.276-279, 1993. ,
Pronuclear morphology evaluation with subsequent evaluation of embryo morphology significantly increases implantation rates, Fertility and Sterility, vol.80, pp.67-74, 2003. ,
Time-course of oocyte activation, pronucleus formation and cleavage in human oocytes fertilized by intracytoplasmic sperm injection, Hum Reprod, vol.9, pp.1743-1748, 1994. ,
The zygote, Human Reproduction, vol.27, pp.22-49, 2012. ,
Preliminary observations on polar body extrusion and pronuclear formation in human oocytes using time-lapse video cinematography, Human Reproduction, vol.12, pp.532-541, 1997. ,
The role of disulfide bond reduction during mammalian sperm nuclear decondensation in vivo, Developmental Biology, vol.101, pp.160-167, 1984. ,
Un Ménage à Quatre: The Molecular Biology of Chromosome Segregation in Meiosis, Cell, vol.112, pp.423-440, 2003. ,
Aneuploidy frequencies in semen fractions from ten oligoasthenoteratozoospermic patients donating sperm for intracytoplasmic sperm injection, Fertility and Sterility, vol.72, pp.472-478, 1999. ,
Triploidy after in vitro fertilization: cytogenetic analysis of human zygotes and embryos, J Assist Reprod Genet, vol.9, pp.68-76, 1992. ,
Aide à l'activation ovocytaire -Un nouvel atout dans le traitement des infertilités masculines sévères ,
, Med Sci (Paris), vol.32, pp.198-203, 2016.
Cohesin SMC1? is required for meiotic chromosome dynamics, sister chromatid cohesion and DNA recombination, Nat Cell Biol, vol.6, pp.555-562, 2004. ,
Cohesin SMC1? is required for meiotic chromosome dynamics, sister chromatid cohesion and DNA recombination, Nature Cell Biology, vol.6, pp.555-562, 2004. ,
Cohesin expression restricted to the pre-dictyate stages of oocyte development provides full fertility and prevents aneuploidy, Curr Biol, vol.20, pp.1529-1533, 2010. ,
Impact of different patterns of sperm chromosomal abnormalities on the chromosomal constitution of preimplantation embryos, Fertility and Sterility, vol.94, pp.1380-1386, 2010. ,
Phospholipase Czeta causes Ca2+ oscillations and parthenogenetic activation of human oocytes, Reproduction, vol.128, pp.697-702, 2004. ,
Cytogenetic analysis of giant oocytes and zygotes to assess their relevance for the development of digynic triploidy, Hum Reprod, vol.17, pp.2388-2393, 2002. ,
The chromosomal constitution of multipronuclear zygotes resulting from in-vitro fertilization, Hum Reprod, vol.12, pp.2257-2262, 1997. ,
Mechanisms giving rise to triploid zygotes during assisted reproduction, Fertil Steril, vol.90, pp.49-55, 2008. ,
Impaired development of zygotes with uneven pronuclear size, Zygote, vol.6, pp.137-141, 1998. ,
Nature of DNA Damage in Ejaculated Human Spermatozoa and the Possible Involvement of Apoptosis1, Biology of Reproduction, vol.66, pp.1061-1067, 2002. ,
Nyboe Andersen A, on behalf of the ESHRE Reproduction and Society Task Force. Demographic and medical consequences of the postponement of parenthood, Human Reproduction Update, vol.18, pp.29-43, 2012. ,
The cumulative dose of gonadotropins used for controlled ovarian stimulation does not influence the odds of embryonic aneuploidy in patients with normal ovarian response, J Assist Reprod Genet, vol.34, pp.749-758, 2017. ,
Chromosomal abnormalities in embryos derived from testicular sperm extraction, Fertility and Sterility, vol.79, pp.30-38, 2003. ,
The chromosomal constitution of embryos developing from abnormally fertilized oocytes after intracytoplasmic sperm injection and conventional in-vitro fertilization, Hum Reprod, vol.12, pp.321-327, 1997. ,
Paternal contribution to embryonic competence, Cent European J Urol, vol.72, pp.296-301, 2019. ,
Chromosomal status of unipronuclear human zygotes following in-vitro fertilization and intracytoplasmic sperm injection, Hum Reprod, vol.10, pp.132-136, 1995. ,
Cellular and molecular mechanisms leading to cortical reaction and polyspermy block in mammalian eggs, Microsc Res Tech, vol.61, pp.342-348, 2003. ,
Ubiquitin tag for sperm mitochondria, Nature, vol.402, pp.371-372, 1999. ,
Depletion of Glutathione during Bovine Oocyte Maturation Reversibly Blocks the Decondensation of the Male Pronucleus and Pronuclear Apposition during Fertilization1, Biology of Reproduction, vol.56, pp.1503-1512, 1997. ,
Aneuploidy and DNA fragmentation in morphologically abnormal sperm, International Journal of Andrology, vol.33, pp.163-179, 2010. ,
Potential effects of age-associated oxidative stress on mammalian oocytes/embryos, Mol Hum Reprod, vol.2, pp.717-724, 1996. ,
Telomere DNA Deficiency Is Associated with Development of Human Embryonic Aneuploidy, PLoS Genet [Internet], vol.7, p.1002161, 2011. ,
The effects of male age on sperm DNA damage in an infertile population, Reproductive BioMedicine Online, vol.15, pp.514-519, 2007. ,
Mitochondrial function in the human oocyte and embryo and their role in developmental competence, Mitochondrion, vol.11, pp.797-813, 2011. ,
Incidence of aneuploid spermatozoa from subfertile men: selected with motility versus hemizona-bound5, Human Reproduction, vol.15, pp.1529-1536, 2000. ,
Cohesin Rec8 is required for reductional chromosome segregation at meiosis, Nature, vol.400, pp.461-464, 1999. ,
Recognition of paternal pronuclei in human zygotes, J Assist Reprod Genet, vol.7, pp.33-37, 1990. ,
Deficit of mitochondria-derived ATP during oxidative stress impairs mouse MII oocyte spindles, Cell Res, vol.16, pp.841-850, 2006. ,
The use of a detailed zygote score after IVF/ICSI to obtain good quality blastocysts: the German experience, Human Reproduction, vol.17, pp.1327-1333, 2002. ,
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, Au moment d'être admis à exercer la médecine, je promets et je jure d'être fidèle aux lois de l'honneur et de la probité
, Mon premier souci sera de rétablir, de préserver ou de promouvoir la santé dans tous ses éléments, physiques et mentaux, individuels et sociaux
, Je respecterai toutes les personnes, leur autonomie et leur volonté, sans aucune discrimination selon leur état ou leurs convictions
, J'interviendrai pour les protéger si elles sont affaiblies, vulnérables ou menacées dans leur intégrité ou leur dignité. Même sous la contrainte
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, Reçu à l'intérieur des maisons, je respecterai les secrets des foyers et ma conduite ne servira pas à corrompre les moeurs
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, Que les hommes et mes confrères m'accordent leur estime si je suis fidèle à mes promesses
, que je sois déshonoré et méprisé si j'y manque