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Master Thesis

Étude épidémiologique des biopsies rénales à l'île de la Réunion de 2015 à 2017

Abstract : Renal biopsy allows renal disease’s classification by providing a definite diagnosis. Today available data mainly concern end stage renal disease (REIN) without data on the epidemiology of renal diseases in Reunion Island. Between 2015 and 2017, 338 native adult kidney biopsies performed on the island were collected with main objective to describe renal pathologies in Reunion Island. Over the 3 years of analysis, renal biopsy was a controlled procedure in terms of complications, with no difference between the detection technique used. The annual biopsy rate has been estimated at 132/million/year with a preponderance in the northern part of the island due to a higher density of nephrologists. Nephrotic syndrome was the first indication in 30% of cases. The four main results are represented by IgA nephropathy (16%), diabetic nephropathy (12.4%), lupus nephropathy (11.2%) and isolated vascular nephropathy (11%). Incidences of the various glomerulopathies are similar to the worldwide incidences with nevertheless a preponderant place of the diabetic nephropathy. Analysis in diabetic patients revealed the criteria for isolated diabetic nephropathy on renal biopsy, namely retinopathy, neuropathy, nephrotic syndrome, younger age and elevated HbA1c. A subgroup of patients with isolated vascular nephropathy without diabetes and with hypertension as a consequence appears to emerge from the analysis. This is the first study to illustrate the main renal pathologies in Reunion Island and it opens up the possibility of additional investigations.
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https://dumas.ccsd.cnrs.fr/dumas-02983215
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Ehshaneraza Asgarali. Étude épidémiologique des biopsies rénales à l'île de la Réunion de 2015 à 2017. Sciences du Vivant [q-bio]. 2020. ⟨dumas-02983215⟩

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