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Master Thesis

Par quels moyens le département de la maintenance/engineering participe-t-il à la qualité du produit pharmaceutique ?

Abstract : The optimization of the maintenance department is expected to become a major concern within the pharmaceutical industry. A maintenance strategy studied and adapted to production sites would enable the pharmaceutical industries to maximize the quality of the drug. In this work, we report the outcomes of a real experience in optimizing maintenance at the Boehringer Ingelheim site in Noventa Padovana, Italy. We have developed a maintenance strategy (TPM) which was born after multiple batches contaminations: a global commitment of these production sites has made it possible/and makes it possible to educate production operators every day on the maintenance of the machines, to educate technicians of maintenance to the importance of preventive and scheduled maintenance of equipment and to acquire this feeling of quality previously thought to be limited within the quality assurance department. We were able to see through this thesis that two components governed the improvement of the efficiency of the maintenance department: a technical component: through the implementation of scheduled maintenance, the implementation of autonomous maintenance, by scheduling corrective maintenance by following a logic and no longer reacting as "firefighters" and a relational/behavioral component: we change the way we work, we work transversally to other departments and no longer individually, our work will have a direct consequence on the quality of our final pharmaceutical product.
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Master Thesis
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https://dumas.ccsd.cnrs.fr/dumas-03072423
Contributor : Ufr Santé Unicaen <>
Submitted on : Wednesday, December 16, 2020 - 11:01:31 AM
Last modification on : Friday, January 29, 2021 - 12:51:40 PM
Long-term archiving on: : Wednesday, March 17, 2021 - 6:46:39 PM

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  • HAL Id : dumas-03072423, version 1

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Fanny Decoutere. Par quels moyens le département de la maintenance/engineering participe-t-il à la qualité du produit pharmaceutique ?. Sciences pharmaceutiques. 2020. ⟨dumas-03072423⟩

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