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Master Thesis

L’hyperplasie congénitale des surrénales à l’adolescence : une revue systématique de la littérature

Abstract : Background: "Congenital adrenal hyperplasia" (CAH) refers to a group of autosomal recessive diseases characterized by enzymatic defects in the biosynthesis of adrenal steroids. The challenges of this chronic disease are multiple. Adolescence is a process during which the subject is subjected to physical and psychological changes. Objective: To determine the physical, psychological and relational impact of CAH in adolescence. Material and Methods: It is an integrative review. Sixteen articles were selected and analysed. Results: Four themes emerged: (1) Physical health (2) Sexual health (3) Psychological health (4) autonomy and therapeutic adherence. There are documented increases in overweight and obesity, hypertension, corticosteroid-induced osteoporosis, gonadal complications, psychological and psychiatric disorders. There are reported decreases in self-esteem and body image, therapeutic adherence, observance and autonomy. However, there are no significant difference in quality of life. Conclusion: The impact of this disease on adolescents’ life is real. Nevertheless, the data collected must be linked to variations in treatment regimens and individual specificities around the world.
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Submitted on : Monday, February 15, 2021 - 3:18:16 PM
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  • HAL Id : dumas-03141797, version 1


Charlotte Raoult. L’hyperplasie congénitale des surrénales à l’adolescence : une revue systématique de la littérature. Gynécologie et obstétrique. 2020. ⟨dumas-03141797⟩



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