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Master Thesis

Association entre syndrome de fragilité et stockage médicamenteux au domicile des personnes âgées en Guadeloupe

Abstract : Introduction: Medication storing, polypharmacy, and frailty, are geriatric conditions that could be related. If true, can medication storage be used by health professionals, other than doctors, to help identify the risk of iatrogenesis? The main objective of this study was to understand the relationship between home medication storing and the risk of frailty in a group of seniors aged 65 and older, living at home in Guadeloupe. Method: The sample consisted of 115 subjects, aged 65 and older, from the epidemiological cohort of the KArukera Study of Aging Drugs Storage (KASADS). Medication storing was considered to be the inventory of any excess of prescribed or over-the-counter (OTC) medication, that could be unused and/or expired. The polypharmacy was defined as the prescription of at least 5 drugs for simultaneous use, and the frail syndrome was assessed by the SOF index. A chi-square test was used in order to compare the number of containers stored, the polypharmacy, and frailty. Results: At last, the sample comprised of 115 seniors, with a 76-year age average (± 7.8) including 67.8% women. 62,6% of the studied population were on polypharmacy. The prevalence of medication storage was 82.6%. Among the participants, 35 individuals, or 30.4%, were considered frail or pre-frail. Those subjects were older than the robust ones (79.5 years old versus 74.5 years old, p = 0.001) and more often exposed to polypharmacy (77.1% versus 56.2%). Polypharmacy was linked to medication storing based on the total number of containers stored (17.5 versus 10.0; p = 0.031) and the number of containers for prescription drugs (9.2 versus 4.3; p = 0.021). No link was established between medication storing [total number of boxes of drugs stored (15.6 versus 14.3; p = 0.724), the total number of containers for prescription drugs (8.3 versus 7; p = 0.566), or the total number of over the counter containers (7.3 against 7.4; p = 0.945)] and the risk of frailty. Conclusion. For this sample of seniors aged 65 and older, supervised by their primary doctor, it was determined that medication storing was not linked to the risk of frailty. Studies of larger samples may confirm or refute these results.
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Master Thesis
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Submitted on : Friday, July 23, 2021 - 5:57:49 PM
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Jordane Chovino, Axelle Boire. Association entre syndrome de fragilité et stockage médicamenteux au domicile des personnes âgées en Guadeloupe. Médecine humaine et pathologie. 2020. ⟨dumas-03298700⟩



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