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Master Thesis

Valeurs normales du strain myocardique global et segmentaire par tissue tracking en IRM et variations en fonction de l’âge et du sexe

Abstract : Background:
Strain measurement by MRI tissue tracking is a new method, more precise, for cardiac function’s evaluation. It is made from routine cine sequences. Normal values are not standardized. The aim of our study is to describe these normal values and to analyze their variations according to age and sex.
Material and Methods:
This is a single-center study carried out at the Rouen hospital center, retrospective, observational. Healthy patients aged 18 to 68 had cardiac MRI with Cine TrueFisp sequences. Global strain measurements and for each left ventricle’s segment were obtained using post-processing software. These values were, then, analyzed by age group and sex. Intra and inter-observer reproducibility was also studied.
Results:
168 patients were included between August 2012 and February 2014. Their mean age was 37.57 years. Global radial peak strain’s average value for the left ventricle is 36.3 +/- 9.1, circumferential peak strain -18 +/- 2.9 and longitudinal peak strain -13.9 +/- 2.8 . Only longitudinal peak strain is significantly correlated with age. The left ventricle global strain’s values are significantly different, in favor of women. The intra-observer reproducibility is 0.94 for the peak strain measurement and the inter-observer reproducibility is 0.75.
Conclusion:
Our study shows myocardial strain’s values in healthy volunteer patients according to sex and age. The deformation is higher in women, regardless of age. The measurement’s variations are, overall, not significant according to the age groups. This method is reproducible, and would allow a better and more precise cardiac function’s analysis.
Document type :
Master Thesis
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https://dumas.ccsd.cnrs.fr/dumas-03340192
Contributor : Claire Leboeuf Connect in order to contact the contributor
Submitted on : Friday, September 10, 2021 - 9:41:57 AM
Last modification on : Tuesday, October 19, 2021 - 4:16:48 PM

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  • HAL Id : dumas-03340192, version 1

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Cécile Ancel. Valeurs normales du strain myocardique global et segmentaire par tissue tracking en IRM et variations en fonction de l’âge et du sexe. Médecine humaine et pathologie. 2021. ⟨dumas-03340192⟩

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