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Master Thesis

Petite taille à 5 ans des enfants nés grands prématurés avec ou sans restriction de croissance fœtale

Abstract : Background : Children born small for gestational age (SGA) full-term and preterm have a higher risk of short stature than their appropriate for gestational age (AGA) peers. Most studies concerning catch-up growth in SGA infants do not take into account fetal growth restriction (FGR) status. The aim was to compare prevalence of short stature at 5 years in children born very preterm with and without FGR. Method : 379 of 924 very preterm (VPT) infants born in La Reunion Island were included. Anthropometric measurements were performed at birth, 2 and 5 years. FGR status was defined by using individualized growth charts by a weight and/or length at birth < 5th percentile. Short stature was defined by height < -2 SDS for age. Results : Twenty-five percent of VPT newborns were classified in the FGR group. Prevalence of short stature at 5 years was 9.6% in the FGR group and 2.1% in the non-FGR group (p = 0.003). FGR infants remained 3 cm shorter and 2 kg lighter than non-FGR infants at 5 and body mass index (BMI) was 1 kg/m² lower (p < 0.001). Rate of thinness (BMI < IOTF 18.5 kg/m²) in the FGR-group was approximately 55%. Conclusion : Most of VPT children showed catch-up growth before 5 years. However, prevalence of short stature was more than four times higher for FGR infants compared to non-FGR.
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Master Thesis
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Submitted on : Thursday, September 16, 2021 - 12:16:39 PM
Last modification on : Tuesday, October 19, 2021 - 5:56:44 PM
Long-term archiving on: : Friday, December 17, 2021 - 6:56:42 PM


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  • HAL Id : dumas-03346394, version 1


Coralie Euvrard. Petite taille à 5 ans des enfants nés grands prématurés avec ou sans restriction de croissance fœtale. Sciences du Vivant [q-bio]. 2021. ⟨dumas-03346394⟩



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