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Master Thesis

Hypotension peropératoire et convulsions postopératoires en pédiatrie : à propos de cinq cas

Abstract : Introduction - Millions of children undergo anaesthesia every year, but several studies have shown a potential neurotoxicity of anaesthetics in the youngest children. Whether this toxicity is direct or a consequence of the effect of anaesthetics on cerebral oxygenation, we have to try and understand its mechanism, in order to be able to prevent further neurological incidents. Methods - This is a retrospective, observational study, between 2009 and 2018 in teaching hospital Necker-Enfants malades, on children who had postoperative seizures, and are still followed for anoxoischemic encephalopathy. We have reviewed their charts to discuss this diagnosis and the responsibility of anaesthesia. Case reports - Five newborns and infants under four months presented with seizures after general anaesthesia. Three of them had prolonged intraoperative hypotension, leading to a low cerebral flow responsible for these seizures. For the other two, it remains difficult to ascertain that an intraoperative hypotension caused the postoperative seizures. Conclusion - Intraoperative hypotension can lead to severe consequences in young infants, but its diagnosis is not always as easy as expected. Therefore, it is of the utmost importance to stay alert during anaesthesia, and to adapt our practice to each patient.
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Master Thesis
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Submitted on : Tuesday, November 9, 2021 - 5:04:01 PM
Last modification on : Wednesday, January 5, 2022 - 3:09:24 AM
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  • HAL Id : dumas-03422019, version 1


Camille Piat. Hypotension peropératoire et convulsions postopératoires en pédiatrie : à propos de cinq cas. Médecine humaine et pathologie. 2019. ⟨dumas-03422019⟩



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