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Master Thesis

Analgesia for labour: a practice survey comparing intermittent automatized bolus versus patient controlled epidural, the alpine study

Abstract : Background: PIEB+PCEA is the new Gold Standard for epidural analgesic administration during labour. Pure PCEA is following the historical trend of dose and secondary effects reduction and might also help patient recover their decision power, improve satisfaction, and better suit those who want to ambulate. This was a pilot study aiming to evaluate if pure PCEA had a similar analgesic profile to PIEB+PCEA. Main criterion: total pain quantity evaluated via the cumulative area under the curve of the hourly maximum numeric evaluating scores (AUC NRS) and comparison of AUC NRS’means. Methods: monocentric retrospective descriptive comparative study on birth room files between February and October 2019. Group 1 (PIEB+PCEA) and group 2 (pure PCEA) received an epidural solution of Levobupivacaine 1mg/cc and Sufentanil 0,25µg/cc, with a possibility of 6ml patient-controlled boluses every 12min. Group 1 received an additional automatized 8ml/h bolus. Results: 73 files analysed, 38 PIEB+PCEA, 35 pure PCEA, analgesic profiles were similar in both groups. Discussion: In this selected population if pure PCEA did as well in term of analgesia, it seemed link to a trend of motor block reduction and improved satisfaction. More studies are expected to validate those results.
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Master Thesis
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https://dumas.ccsd.cnrs.fr/dumas-03468721
Contributor : Jean-Hugues Morneau Connect in order to contact the contributor
Submitted on : Tuesday, December 7, 2021 - 12:03:26 PM
Last modification on : Saturday, January 1, 2022 - 3:33:23 AM

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  • HAL Id : dumas-03468721, version 1

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Martin Dupuis. Analgesia for labour: a practice survey comparing intermittent automatized bolus versus patient controlled epidural, the alpine study. Human health and pathology. 2020. ⟨dumas-03468721⟩

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