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Master Thesis

Étude comparative de la métacognition synthétique dans les troubles du spectre de la schizophrénie et les troubles du spectre de l’autisme sans déficience intellectuelle

Abstract : Background: Unique deficits in synthetic metacognition have been found in schizophrenia compared with other conditions and controls. Higher metacognition is associated with better patient’s outcomes. To date no study has compared metacognition in schizophrenia and ASD and its potential association with recovery-related outcomes. Objectives: The objectives of the present study are: i) to compare metacognition in schizophrenia and ASD; ii) to assess the correlations between basic metacognition, insight, cognitive function and recovery-related outcomes. Methods: 56 outpatients with schizophrenia and ASD were recruited from two French Centers of Reference for Psychiatric Rehabilitation. Evaluation included, Metacognitive Assessment Scale-Abbreviated (MAS-A), standardized scales for self-esteem, quality of life, satisfaction with life, wellbeing, and personal recovery and a large cognitive battery. Results: The internal consistency for the MAS-A was α=0.89. Compared with those with schizophrenia, participants with ASD had higher self-reflectivity (p=0.025; OR=1.38 [1.05- 1.86]) in non-adjusted univariate analyses. This association became non-significant after adjusting for gender, overall functioning and depressive symptoms. Metacognition correlated positively with executive functions and satisfaction with life in bivariate analyses. Basic metacognition (self-reflectivity score > 4) was associated in adjusted analyses with abstraction abilities (WAIS-IV matrix subscale score; p=0.042; OR=1.78 [1.02-3.11]). Conclusion: Comparable impairments in synthetic metacognition were found in ASD and schizophrenia patients. The relationships between metacognition, insight, depression and recovery-related outcomes in ASD should be further investigated. The correlations with executive functions and satisfaction with life suggest potential therapeutic implications of cognitive remediation in ASD.
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Master Thesis
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https://dumas.ccsd.cnrs.fr/dumas-03469065
Contributor : Jean-Hugues Morneau Connect in order to contact the contributor
Submitted on : Tuesday, December 7, 2021 - 2:49:43 PM
Last modification on : Saturday, January 1, 2022 - 3:33:23 AM

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  • HAL Id : dumas-03469065, version 1
  • PPN : 248868586

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Aude Martin. Étude comparative de la métacognition synthétique dans les troubles du spectre de la schizophrénie et les troubles du spectre de l’autisme sans déficience intellectuelle. Médecine humaine et pathologie. 2020. ⟨dumas-03469065⟩

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