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Master Thesis

Les diagnostics différentiels de COVID-19 graves en zone tropicale lors de la première vague : l'expérience de La Réunion

Abstract : Background : Little was known about the differential diagnoses of coronavirus disease 2019 (COVID-19) and tropical infectious diseases during the frst wave of the pandemic, The aim of this study was to identify the differential diagnoses of severe COVID-19 and the distinguishing characteristics of critically ill COVID-19 patients in Reunion Island to help improve the triage and management of patients in this tropical setting. Methods : This retrospective observational study was conducted from 11 March to 4 May 2020 in the only intensive care unit (ICU) authorized to manage COVID-19 patients in Reunion Island, a French overseas department located in the Indian Ocean region, All patients with unknown COVID-19 status were tested by polymerase chain reaction (PCR) on ICU admission; those who tested negative were transferred to the COVID- 19-free area of the ICU. Results : Over the study period, 99 patients were admitted to our ICU, A total of 33 patients were hospitalized in the COVID-19 isolation ward, of whom 11 were positive for COVID-19, The main differential diagnoses of severe COVID-19 were: community-acquired pneumonia, dengue, leptospirosis causing intra-alveolar hemorrhage, and cardiogenic pulmonary edema. No distinguishing clinical, biological, or radiological characteristics were found between the 2 groups of patients. All COVID-19-positive patients had recently traveled or been in contact with a recent traveler. Conclusions : In Reunion Island, dengue and leptospirosis are key differential diagnoses of severe COVID-19, and travel is the only distinguishing characteristic of COVID-19-positive patients. Our fndings apply only to the particular context of Reunion Island at this time of the epidemic.
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Master Thesis
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Submitted on : Thursday, December 9, 2021 - 11:18:25 AM
Last modification on : Wednesday, May 11, 2022 - 8:24:08 AM


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  • HAL Id : dumas-03472204, version 1


Pauline Krol. Les diagnostics différentiels de COVID-19 graves en zone tropicale lors de la première vague : l'expérience de La Réunion. Sciences du Vivant [q-bio]. 2021. ⟨dumas-03472204⟩



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