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Master Thesis

Répercutions bucco-dentaires de l'hypophosphatasie

Abstract : Hypophosphatasia is an inherited genetic disease characterized by a deficit in alkaline phosphatase activity. Its clinical spectrum is extremely variable, and includes skeletal and dental malformations, depending on the severity of the disease. Oral repercussions are present at all stages of the disease, and affect all mineralized dental tissues. The early loss of teeth is linked to an aplasia of the acellular cementum, the area of insertion of the periodontal ligament. Other dental tissues are sometimes affected, and include hypomineralization of the alveolar bone, dentin and enamel. The pediatric dentist is in a privileged position in the early diagnosis of hypophosphatasia.
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Master Thesis
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Submitted on : Monday, January 10, 2022 - 2:38:37 PM
Last modification on : Friday, January 14, 2022 - 3:29:56 AM
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  • HAL Id : dumas-03519421, version 1


Samantha Chevalet. Répercutions bucco-dentaires de l'hypophosphatasie. Chirurgie. 2020. ⟨dumas-03519421⟩



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