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Master Thesis

Microbiome cutané physiologique et pathologique : étude du marché français des solutions cosmétiques

Abstract : The human skin, large surface for exchange and protection, is home to many microorganisms: bacteria, fungi and viruses. Among this population, we distinguish beneficial organisms and potentially pathogenic organisms. This population is studied through its genetic material called microbiome. The microbiome is dynamic and varies according to intrinsic and extrinsic parameters. Thus, each microbiome is unique. Recent scientific studies have been carried out and have made possible the characterization of physiological and pathological skin microbiome. Those studies have highlighted the protective role of the microscopic populations through their educational and collaborative roles with the host immune system. These studies have also established that an imbalance in the microbiome can contribute to the development and maintenance of inflammatory skin diseases. Among highly prevalent dermatoses in France, we can cite atopic dermatitis and acne. In atopic dermatitis, there is a dysbiosis in favor of the Staphylococcus aureus bacteria, while in the case of acne, the role of Cutibacterium acnes is no longer in doubt. In the management of these dermatoses, the use of adapted adjuvant cosmetics is essential. For these several reasons, skincare and hygiene products have been developed with the objective of respecting this flora, in a physiological context, or even rebalancing it, in a pathological context. The products formulated involve neutral formulas respectful of the microbiome sometimes containing prebiotic, probiotic and post-biotic active ingredients to modulate these populations. This new and rapidly expanding offer constitutes a dynamic and promising market supported by diversified brands. To meet a challenging demand, these products must be of exemplary quality and prove their effectiveness.
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Master Thesis
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https://dumas.ccsd.cnrs.fr/dumas-03545266
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Submitted on : Thursday, January 27, 2022 - 10:41:25 AM
Last modification on : Saturday, January 29, 2022 - 3:38:52 AM

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Amayelle Dia. Microbiome cutané physiologique et pathologique : étude du marché français des solutions cosmétiques. Sciences du Vivant [q-bio]. 2021. ⟨dumas-03545266⟩

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