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Master Thesis

Devenir global à 2 ans des enfants diagnostiqués RCIU isolés en anténatal au centre pluridisciplinaire de diagnostic prénatal de La Réunion

Abstract : Introduction : The IUGR (Intra Uterine Growth Retardation) is a major issue in public health, indeed it’s the second cause of perinatal morbidity and mortality in France and even if the future of IUGR diagnosed postnatal is well known, we have few data on the fate of those diagnosed prenatal. It is therefore difficult for us to provide precise information to parents concerning the fate of their child when we see them on DAN ultrasound (Ante Natal Diagnosis). Main objective: To evaluate the psychomotor outcome at 2 years of isolated IUGRs diagnosed prenatal by referring sonographers. Secondary objective: To assess the appearance of associated pathologies in the postnatal period. Method: We included all patients whose fetuses were diagnosed with IUGR isolated at antenatal diagnosis and presented to the CPDP (Pluridisciplinary Center for Prenatal Diagnosis) between December 1, 2015 and July 31, 2019. Then we called the parents to answer a validated questionnaire that assessed the neurodevelopmental outcome of their children at 2 years old, then we collected all the pathologies discovered postnatal. Results: 110 children were included of whom only 6.4% (n = 7/110) had abnormal scores with lower scores in the language field (77.2% optimal score). At 2 years, 70.9% (n = 78) had normal weight compared to other children of their age. Postnatal pathologies were discovered in 11.8% (n = 13) of them and 20% (n = 22) had been re-hospitalized, in most cases for bronchiolitis. Conclusion: The evolution of these isolated IUGR children diagnosed prenatal is generally good at 2 years; thus the information given to parents during the diagnosis of isolated IUGR antenatal, even if it must expose the risk of an infectious or genetic origin of IUGR, must nevertheless be reassuring about the overall outcome at 2 years.
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Master Thesis
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Submitted on : Tuesday, February 1, 2022 - 6:17:55 AM
Last modification on : Saturday, February 12, 2022 - 3:26:32 AM
Long-term archiving on: : Tuesday, May 3, 2022 - 8:44:08 AM


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  • HAL Id : dumas-03550314, version 1


Lola Mariani. Devenir global à 2 ans des enfants diagnostiqués RCIU isolés en anténatal au centre pluridisciplinaire de diagnostic prénatal de La Réunion. Sciences du Vivant [q-bio]. 2021. ⟨dumas-03550314⟩



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