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Master Thesis

Revue de la littérature des causes organiques de premier épisode psychotique des patients âgés de 15 à 30 ans

Abstract : First-episode psychosis (FEP) is the first presentation of a patient's psychotic symptoms. Psychosis can be a symptom of a mental illness or a physical condition. Literature reports an organic origin in 5.6% of FEP. However, neither international nor national consensus exist, thus leading to wide disparity in practices and some misdiagnostis. This thesis aims to identify organic diseases triggering first-episode psychosis in patients aged 15 to 30 years. A systematic literature review was performed and combined with selective and specific reviews for each cause, resulting in 569 article’s inclusions. Ninety etiologies or groups of etiologies were identified including neurological, autoimmune, genetic, endocrine, gynecological, gastrointestinal, inflammatory, metabolic, and infectious disorders. Authors clinical practice recommendations and indicators were identified for specific diseases. For each identified disorder, systematic literature review, meta-analyses and cost-effectiveness analyses should be further performed to establish French Guidelines. This thesis proposes paraclinical tests to be carried out in any patient aged 15 to 30 years presenting FEP, as well as indicators that should lead to the prescription of additional examinations.
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Submitted on : Monday, February 28, 2022 - 11:31:00 AM
Last modification on : Saturday, April 9, 2022 - 3:43:43 AM


TESNIERES Charles Psy.pdf
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  • HAL Id : dumas-03590917, version 1


Charles Tesnières. Revue de la littérature des causes organiques de premier épisode psychotique des patients âgés de 15 à 30 ans. Médecine humaine et pathologie. 2021. ⟨dumas-03590917⟩



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