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Master Thesis

L’influence des conflits d’intérêt sur les résultats des méta analyses sur l’homéopathie

Abstract : Background: Nowadays homeopathy is often subject to debate. It is a controversial therapy that faces skepticism from part of the scientific community. This work intends to explore the possible relationship between the potential conflicts of interest related to a meta-analysis and its results. Methods: PubMed was searched for all studies performed on homeopathy. Meta-analyses were selected and the information was extracted by two independent readers. All estimates (OR, RR, MD, SMD) were extracted from the selected meta-analyses. MD and SMD were transformed to approximate ORs through the Chinn method. Subgroup analyses were performed to assess the influence of moderating factors such as possible conflict of interest, the nature of the sponsor (industrial or academic), and the quality of included studies. Results: We identified a total of 664 studies through our electronic database searches. After removing duplicates, assessing titles and studying full-text articles, we included 18 meta-analyses. The results on the efficiency of homeopathy are not statistically different whether there is a conflict of interest (OR = 0,65) or not (OR = 0,61) considering the random effect model. Conclusion: This meta-analysis does not demonstrate the efficiency of homeopathy nor the influence of the conflicts of interests on the results of homeopathy meta-analyses. Further research should be conducted to conclude.
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Master Thesis
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https://dumas.ccsd.cnrs.fr/dumas-03606364
Contributor : Jean-Hugues Morneau Connect in order to contact the contributor
Submitted on : Monday, March 28, 2022 - 12:15:12 PM
Last modification on : Monday, April 11, 2022 - 5:02:39 PM

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  • HAL Id : dumas-03606364, version 1

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Aminata Diallo, Agathe Coste. L’influence des conflits d’intérêt sur les résultats des méta analyses sur l’homéopathie. Sciences pharmaceutiques. 2021. ⟨dumas-03606364⟩

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