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Master Thesis

Mise au point actualisée de l'utilisation des antibiotiques en endodontie

Abstract : Endodontic infections, are polymicrobial, and in most cases, the prescription of antibiotics is empirical. The primary intention is to achieve drainage without additional antibiotics. Adjunctive antibiotic treatment may be necessary in the prevention of the spread of infection, to guarantee the success of the treatment and to avoid local or systemic complications. Medically compromised patients are more susceptible to complication arising from endodontics infections and antimicrobials have a more specific role in their treatment. Therefore, antibioprophylaxy (followed by antibiotherapy or not) should be considered in patients having systemic diseases with compromised immunity or in patients with a localized congenital or acquired altered defence capacity (such as patients with infective endocarditis, diabetes). Amoxicillin, possibly combined with metronidazole to cover anaerobic strains, is still effective in most cases. However, amoxicillin (alone or together with clavulanic acid) is recommended because of better absorption and lower risk of side effects. In case of confirmed penicillin allergy, lincosamides such as clindamycin are the drug of choice. The overuse of antibiotics and the emergence of antibiotic-resistant bacterial strains is a global concern.
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Master Thesis
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Contributor : Ufr d'Odontologie Amu Connect in order to contact the contributor
Submitted on : Wednesday, April 13, 2022 - 3:07:06 PM
Last modification on : Friday, April 15, 2022 - 3:30:52 AM


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  • HAL Id : dumas-03640415, version 1


Guilhem Paufique. Mise au point actualisée de l'utilisation des antibiotiques en endodontie. Chirurgie. 2021. ⟨dumas-03640415⟩



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