Patterns of Methylphenidate Use and Assessment of Its Abuse among the ă General Population and Individuals with Drug Dependence - Archives ouvertes de l'Economie Accéder directement au contenu
Article Dans Une Revue European Addiction Research Année : 2016

Patterns of Methylphenidate Use and Assessment of Its Abuse among the ă General Population and Individuals with Drug Dependence

Elisabeth Frauger
  • Fonction : Auteur
Despina Amaslidou
  • Fonction : Auteur
Michel Spadari
  • Fonction : Auteur
Veronique Allaria-Lapierre
  • Fonction : Auteur
David Braunstein
  • Fonction : Auteur
Vincent Sciortino
  • Fonction : Auteur
Xavier Thirion
  • Fonction : Auteur
Samira Djezzar
  • Fonction : Auteur

Résumé

Purpose: The aim of this study was to describe the extent of ă methylphenidate (MPH) abuse and characterize its patterns by following ă several cases involving intravenous administration of crushed MPH ă tablets. Methods: First, a drug reimbursement database (covering 4 ă million inhabitants) was explored to assess the magnitude of MPH abuse ă among the general population, and second, a specific study based on ă individuals with drug dependence was performed to describe abusers' ă characteristics (n = 64), patterns of abuse and clinical implications. ă Results: From 2005 to 2011, the number of patients who were dispensed ă MPH at least once increased by 166%. The patients with `deviant' ă patterns of MPH consumption were mainly male adults with opiate ă maintenance treatment reimbursements. MPH abusers had precarious living ă conditions. Half of them consumed MPH daily by intravenous route and ă reported amphetamine-like effects (cardiovascular events, weight loss, ă psychiatric adverse events). Conclusion: Given the increase of MPH use, ă it is important to warn the scientific community about possible MPH ă abuse, especially in individuals with drug dependence. This study has ă facilitated public health intervention and dissemination of information ă related to MPH abuse among health care professionals at local and ă national levels. (C) 2015 S. Karger AG, Basel
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Dates et versions

hal-01482640 , version 1 (03-03-2017)

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Citer

Elisabeth Frauger, Despina Amaslidou, Michel Spadari, Veronique Allaria-Lapierre, David Braunstein, et al.. Patterns of Methylphenidate Use and Assessment of Its Abuse among the ă General Population and Individuals with Drug Dependence. European Addiction Research, 2016, 22 (3), pp.119-126. ⟨10.1159/000439273⟩. ⟨hal-01482640⟩

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