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Master Thesis

Douleur et exacerbation de Bronchopneumopathie Chronique Obstructive : étude descriptive et comparative à 30 jours (étude Morpho-COPD 1b, résultats préliminaires)

Abstract : Introduction: Chronic pain is common in patients with Chronic Obstructive Pulmonary Disease (COPD). The pain intensity may increase during acute episodes of exacerbations. The aim of this cohort study was to compare the pain during exacerbation and stable COPD. Methods: Patients in acute exacerbation of COPD were included in the emergency department. The intensity and characteristics of pain were evaluated from the Short-Form McGill Pain Questionnaire (SF-MPQ) and the Brief Pain Inventory (BPI). Assessment of respiratory status, anxiety and depression, and clinical and biological data, defining the severity of exacerbation, were also collected. A 30-day follow-up visit, after a return to the stable state of COPD, allowed the realization of Respiratory Functional Exploration and the same questionnaires. Results: Data from 21 patients enrolled between 01.12.2015 and 01.07.2016, were studied in this interim analysis. The pain intensity, measured by the total score of the SF-MPQ, was higher in exacerbation than stable phase: 19 [9-31] vs. 5 [0-12] (p = 0.001). The descriptive characteristics and location of pain were different between the two phases. Dyspnea and anxiety during exacerbations were correlated with pain intensity (respectively, r = 0.529; p = 0.014 and r = 0.473; p = 0.030). However, no correlation was found between the pain and the severity of the exacerbation or severity of COPD. Conclusion: These results emphasize the need for specific treatments of pain patients during exacerbations of COPD.
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Master Thesis
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https://dumas.ccsd.cnrs.fr/dumas-01385654
Contributor : Jean-Hugues Morneau <>
Submitted on : Friday, October 21, 2016 - 5:32:39 PM
Last modification on : Wednesday, July 15, 2020 - 8:58:04 AM

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  • HAL Id : dumas-01385654, version 1

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Ludivine Duc. Douleur et exacerbation de Bronchopneumopathie Chronique Obstructive : étude descriptive et comparative à 30 jours (étude Morpho-COPD 1b, résultats préliminaires). Médecine humaine et pathologie. 2016. ⟨dumas-01385654⟩

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