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Master Thesis

ALIVE : registre alpin du gilet défibrillateur portable

Abstract : Ventricular arrhythmias are a common cause of sudden death. The wearable cardioverter defibrillator (WCD) is a non-invasive preventive solution to detect and treat them. The objectives of this study were to evaluate the efficacy and safety of the WCD as well as to identify the predictive factors of an electric shock and of an evolution towards an implantable cardioverter defibrillator (ICD). This is a retrospective, descriptive, multicenter study conducted in 4 french centers in Grenoble, Valence, Chambéry and Annecy. The inclusion criterion was the installation of a GDP between June 2015 and June 2020 within the reimbursed indications. Rhythmic and statistical alerts were recorded by the WCD. Medical history and follow-up were collected in the medical files. The primary endpoint was the occurrence of an appropriate shock and its effectiveness as well as the occurrence of an inappropriate shock and its consequences. Out of 263 patients, 6247 events were recorded ; 30 sustained ventricular tachycardias (VT) in 6 patients (2.3%). 3 patients (1.1%) required an electric shock with effective reduction of the arrhythmia at first shock. 23 shocks for sustained VT were voluntarily interrupted in the other 3 patients. 6193 events were artefacts, causing 2 inappropriate shocks in 2 patients (0.8%). The median wearing compliance was 23.5 hours per day. Predictive factors for electric shock and implantation of an ICD have been identified. This study confirms the efficacy and safety of the WCD in a real Life population with a high level of adherence.
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Master Thesis
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Submitted on : Friday, October 8, 2021 - 5:19:15 PM
Last modification on : Monday, October 18, 2021 - 3:37:25 PM


  • HAL Id : dumas-03371561, version 1


Benjamin Casez. ALIVE : registre alpin du gilet défibrillateur portable. Médecine humaine et pathologie. 2021. ⟨dumas-03371561⟩



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