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Master Thesis

Embolie Gazeuse : Epidémiologie au bloc opératoire et analyse des outils de Diagnostic

Abstract : Background: Air embolism is a condition defined by the passage of air bubbles in bloodstream following a vascular breach. This condition is known and well described although diagnosing it and knowing its epidemiology is difficult. Our study aims at finding and assessing clinical and biological criterions which would be specific of air embolism. These criterions may be associated in a clinical diagnostic score. Method: The study is parted in two and comes after physiopathological explanations on air embolism. The first part is a prospective epidemiologic record, realized over a defined period within operating room of one hospital complex reporting all procedures considered “at risk” of air embolism. The second part is a case control study dealing with air embolism cases. The cases are recruited retrospectively and compared to prospective controls recruited in part one. Results: The association of three clinical criterion: drop of 25% of ETCO2, desaturation < 90% and haemodynamic collapse was associated to diagnostic of air embolism with a PPV of 78%. Odds ratios between the 3 criterion and 0 criterion and between 3 and 1 or 2 criterion were as well significantly (p<0.0001) higher in the 3 criterion group emphasizing the clinical relevance and usefulness of such an association.
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Master Thesis
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https://dumas.ccsd.cnrs.fr/dumas-03429069
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Submitted on : Monday, November 15, 2021 - 2:18:13 PM
Last modification on : Wednesday, November 24, 2021 - 3:41:01 AM

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  • HAL Id : dumas-03429069, version 1

Citation

Pierre Caro. Embolie Gazeuse : Epidémiologie au bloc opératoire et analyse des outils de Diagnostic. Sciences du Vivant [q-bio]. 2021. ⟨dumas-03429069⟩

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