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Master Thesis

Mesure continue du glucose‎ : ce système a-t-il répondu aux attentes du patient dans la prise en charge de son diabète ?

Abstract : Continuous glucose monitoring proved its effectiveness in reducing HbA1c and glycemic variability without increasing hypoglycemia number. The main objective of this single-center retrospective and prospective study is to assess the initial expectations of patients fitted with a sensor and analyze this service from a questionnaire. Secondary objectives consist in evaluating after three months of use patient's behavioral changes, metabolic consequences (HbA1c) and severe hypoglycemia number with the use of automated insulin suspension. Between April 2009 and July 2012, in Grenoble University Hospital, 35 adult patients with type 1 diabetes were equipped of sensors. 33 of them have been treated with continuous subcutaneous insulin infusion, with a mean baseline HbA1c of 8.1 ± 1.4%. The predominant satisfaction is hypoglycemia prevention (100% of patients) and secondarily hyperglycemia control (88%). 51% of patients have dropped out, mostly related to the anxiety generated by alerts and technical difficulties. After 3 months of use the average number of bolus per day increased by 56% (p = 0.06). The temporary insulin suspension was also increased by 34% (p = 0.09). The mean decrease in HbA1c observed at 3 months was 0.31% (n = 23) and 1.15% for patients with HbA1c > 9%. None of the 17 patients fitted with automated insulin suspension had severe hypoglycemia. Therefore, this system can help the patient when it is associated with a specific therapeutic education program.
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Master Thesis
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Submitted on : Monday, October 22, 2012 - 10:52:16 AM
Last modification on : Tuesday, May 11, 2021 - 11:36:17 AM
Long-term archiving on: : Saturday, December 17, 2016 - 2:50:15 AM


  • HAL Id : dumas-00744012, version 1
  • PPN : 164900977


Anne-Laure Coulon. Mesure continue du glucose‎ : ce système a-t-il répondu aux attentes du patient dans la prise en charge de son diabète ?. Médecine humaine et pathologie. 2012. ⟨dumas-00744012⟩



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