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Master Thesis

De l'Orient à l'Occident, une plante hallucinogène‎ : le Khat

Abstract : Khat (Catha edulis Forsk.), Family Celastraceae, is a plant endemic to East Africa and Yemen. Traditionally consumed during long chewing sessions, its leaves are used for their euphoric and stimulating properties. Cathinone, khat main alkaloid responsible for these effects, leads to various adverse effects of three types : short-term (insomnia, lethargy, depression), medium and long term (hypertension, diabetes, oral diseases, cancers, etc... ). The direct link between khat and illness is not always highlighted, but is not excluded. The use of this plant as an anorectic or against smoking cessation is now obsolete. Nevertheless, there is keen interest in cytotoxic alkaloids of this plant to develop new therapeutics against cancer. Synthetic drugs derived from khat are highly developed in Western countries the last few years. Thus, the use of mephedrone increases in young people due to the decrease in the quality of other drugs and an attractive price. It is also noteworthy that the consumption of Khat has social implications, particularly in family life and the economic sphere. On legislation towards this hallucinogenic plant, it is not uniform throughout the world; in France, khat was registered on the list of narcotics in 1957.
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Master Thesis
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Submitted on : Thursday, January 24, 2013 - 11:39:59 AM
Last modification on : Tuesday, May 11, 2021 - 11:36:17 AM
Long-term archiving on: : Thursday, April 25, 2013 - 3:52:13 AM

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  • HAL Id : dumas-00780547, version 1

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Nicolas Zakar. De l'Orient à l'Occident, une plante hallucinogène‎ : le Khat. Sciences pharmaceutiques. 2013. ⟨dumas-00780547⟩

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