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Master Thesis

Étude des caractéristiques vasculaires et tensionnelles des patients porteurs d'une dysplasie fibromusculaire (à partir des patients inclus dans l'étude Arcadia-Profile au CHU de Grenoble)

Abstract : Introduction. Fibromuscular dysplasia (FMD) is an idiopathic disease which primarily affects the renal arteries followed by the supra-aortic trunks (SAT). Women are most affected by this disease. Method. We conducted a descriptive study to analyze vascular and blood pressure characteristics of the patients with FMD at Grenoble University Hospital between June 2010 and July 2013. During this period, we gathered data on 101 patients. Results. Our study confirmed the female predominance of the disease (86.1%), affecting all ages of life (mean age 57.3 years). The circumstances of discovery were varied, with a higher prevalence of hypertension in renal presentation. The FMD was found for two-thirds of patients in abdominal and pelvic territories, with a predominant multifocal form (77.2%). Renal localization was the most frequent (83.2%). Abdominopelvic and cervicoencephalic involvment was found in 42.6% of patients, with an average number of localisations of 3.11. The radiological assessment to confirm the diagnosis was a combination of CT and Doppler imaging (47.5% vs. 34.7% for CT only). Angiography was performed in less than 5% of cases in persistent diagnostic doubt, however, that examination was essential for angioplasty of the renal arteries (44% of stenoses were dilated). Conclusion. The population affected by the FMD is predominantly prime-aged women. Multiple locations were frequent and key review of morphological assessment was CT.
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Master Thesis
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https://dumas.ccsd.cnrs.fr/dumas-00876554
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Submitted on : Thursday, October 24, 2013 - 5:58:09 PM
Last modification on : Tuesday, May 11, 2021 - 11:36:17 AM
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Benoît Berthoud. Étude des caractéristiques vasculaires et tensionnelles des patients porteurs d'une dysplasie fibromusculaire (à partir des patients inclus dans l'étude Arcadia-Profile au CHU de Grenoble). Médecine humaine et pathologie. 2013. ⟨dumas-00876554⟩

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