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Master Thesis

À propos des cas de grippe grave hospitalisés en réanimation à La Réunion en 2014

Abstract : Introduction: Influenza is a frequent condition that can cause death among high-risk patients. Each year in Reunion, it causes severe cases leading to admission to ICU and fatalities. Our objective is to describe severe cases of influenza infections admitted in ICU in Reunion in 2014 and to draw attention to the flaws in the preventive measures. Patients: A retrospective, observational case report study was conducted in hospitalized patients with severe influenza confirmed by RT-PCR in ICUs in Reunion Island in 2014. Results: Thirty-one cases of severe influenza were reported in 2014. Twenty-four patients (77,4%) had at least one risk factor for complication from influenza infections. Among them, eleven (35,5%) people were 65 years-old or older. Main risk factors were respiratory diseases (41,9%), diabetes mellitus (32,3%) and cardiac diseases (25,8%). The most common organ failures were respiratory (80,6%) – including 10 acute! respiratory distress syndromes – and hemodynamic (61,3%). Influenza virus B was identified in most cases (51,6%). Sub-types A(H1N1)pdm09 and A(H3N2) viruses were identified respectively in 38,7% and 9,6%. Not a single patient had been immunized prior to hospitalization. Neuraminidase inhibitors were prescribed to 14 patients with a 4 days delay (extremes=[1-14]) after onset of illness. To our knowledge, no antivirals were prescribed in ambulatory care before hospitalization. Conclusion: In Reunion, influenza vaccination coverage of high-risk patients is very low and the antiviral medications are under prescribed in ICU as well as at the primary care level. Enhancing these measures would help avoiding influenza-related severe illnesses and fatalities. Information to the public and to health care providers, especially GP, seems to be the best measures to achieve it. The role of the GP in preventing severe cases of influenza must be emphasised.
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Master Thesis
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https://dumas.ccsd.cnrs.fr/dumas-01247982
Contributor : Bu Carreire Université de Bordeaux <>
Submitted on : Wednesday, December 23, 2015 - 11:30:54 AM
Last modification on : Friday, October 23, 2020 - 5:02:45 PM
Long-term archiving on: : Thursday, March 24, 2016 - 12:11:11 PM

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Xavier Hoarau. À propos des cas de grippe grave hospitalisés en réanimation à La Réunion en 2014. Médecine humaine et pathologie. 2015. ⟨dumas-01247982⟩

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