Skip to Main content Skip to Navigation
Master Thesis

Structure-Function Relationships With Spectral-Domain Optical Coherence Tomography Retinal Nerve Fiber Layer and Optic Nerve Head Measurements

Abstract : Purpose: To evaluate the regional structure–function relationship between visual field sensitivity and retinal nerve fiber layer (RNFL) thickness and optic nerve head (ONH) measurements using spectral-domain optical coherence tomography (SD-OCT). Results: 142 eyes of 142 subjects were included. The correlations (rÇ) between RNFL thickness and visual field sensitivity ranged from 0.07 to 0.60, between Cirrus-based neuroretinal rim thickness and visual field sensitivity ranged from 0.15 to 0.49, and between BMO-MRW and visual field sensitivity ranged from 0.24 to 0.66. The structure–function correlations were stronger with BMO-MRW than with Cirrus-based neuroretinal rim thickness. The largest areas under the receiver operating curve were seen for rim area (0.926 [95% confidence interval 0.875,0.977]; p<.001) in eyes with glaucoma and for average RNFL (0.863 [0.769,0.957]; p<.01) in eyes with suspected glaucoma. Conclusions: The structure–function relationship was significantly stronger with BMO-MRW than other ONH SD-OCT parameters. The best diagnostic capabilities were seen with rim area and average RNFL.
Document type :
Master Thesis
Complete list of metadatas

Cited literature [32 references]  Display  Hide  Download

https://dumas.ccsd.cnrs.fr/dumas-01254656
Contributor : Jean-Hugues Morneau <>
Submitted on : Tuesday, January 12, 2016 - 3:18:46 PM
Last modification on : Wednesday, July 15, 2020 - 8:58:04 AM
Long-term archiving on: : Friday, November 11, 2016 - 1:50:01 AM

Identifiers

  • HAL Id : dumas-01254656, version 1

Citation

Frédéric Pollet-Villard. Structure-Function Relationships With Spectral-Domain Optical Coherence Tomography Retinal Nerve Fiber Layer and Optic Nerve Head Measurements. Human health and pathology. 2015. ⟨dumas-01254656⟩

Share

Metrics

Record views

162

Files downloads

258