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Master Thesis

Morts foetales in utero : facteurs étiologiques, rôle du diabète et de l'obésité : étude cas-témoins monocentrique réalisée sur la période 2008-2014

Abstract : Objective : We aimed at investigating the role played by different risks factors on the incidence of stillbirth, such as diabete and obesity. Methods and design: Cases were women with singleton or twins, born after 22 weeks of gestation between 2008 and 2014 in the university hospital center of Caen, France. 3 controls were matched per case. Matching was based on maternal age and year of death. Datas were obtained through the program for medicalization of information systems and the observatory of infant and fetal mortality of the Lower-Normandy perinatal network. A multivariable regression model was developped, adjusted on known risk factors for stillbirth and significant risk factors identified in the current study. Adjusted odds ratio and 95% confidence intervals were calculated with this multivariable model. Results : 137 stillbirth were listed on this period. Obesity (ORa=1,90; 1,04-3,46), multiparity (ORa=2,84; 0,90-8,97), gemellary pregnancy (ORa=47,47; 6,20-363,63), maternal tabagism (ORa= 2,60; 1,28-5,26) and intra uterine growth restriction (ORa=6,70; 3,00-14,93) were found as independant risk factor of stillbirth. Conclusion : Chronicle diabete was not found as an independant risk factor for stillbirth in our study. However, obesity was associated with a significant increase in the risk of stillbirth.
Mots-clés : Foetus -- Mort Diabètes
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https://dumas.ccsd.cnrs.fr/dumas-01328042
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Submitted on : Tuesday, June 7, 2016 - 2:41:40 PM
Last modification on : Wednesday, December 4, 2019 - 9:52:02 AM

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  • HAL Id : dumas-01328042, version 1

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Maxime Beuzelin. Morts foetales in utero : facteurs étiologiques, rôle du diabète et de l'obésité : étude cas-témoins monocentrique réalisée sur la période 2008-2014. Gynécologie et obstétrique. 2016. ⟨dumas-01328042⟩

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