Skip to Main content Skip to Navigation
Master Thesis

Complications vasculo-placentaires chez les femmes enceintes infectées par le VIH : une étude cas-témoin

Abstract : Background: Data from international literature suggest a link between HIV infection and placental vascular complications during pregnancy. Current studies on the subject are conflicting. Objective: The aim of the study was to evaluate the incidence of placental vascular complications during pregnancy among HIV+ and HIV- patients. Study Design: It is a single-center case-control study comparing the rates of gestational hypertension, preeclampsia, eclampsia and vascular intrauterine growth retardation from 280 HIV+ and 560 HIV- patients matched by age, parity and geographical origin. Results: The rate of placental vascular complications was not statistically different between HIV+ and HIV- patients: 7.5% vs 9.8%, respectively (p = 0.27). HIV+ patients have a significant increase in overall prematurity rate: 18.6% vs 8.0%, p <0.0001 and a significant decrease in birthweight for gestational age: 41.6th percentile vs 46.6th percentile, p = 0.02. Conclusion: This study does not observe difference in the incidence of placental vascular complications between HIV + and HIV- patients. The significant increase in prematurity and low birth weight among HIV + patients has to be explored by further specific studies.
Document type :
Master Thesis
Complete list of metadata

Cited literature [25 references]  Display  Hide  Download
Contributor : Université Paris Descartes - Scd Connect in order to contact the contributor
Submitted on : Friday, February 17, 2017 - 10:09:08 AM
Last modification on : Thursday, November 25, 2021 - 3:45:45 AM
Long-term archiving on: : Thursday, May 18, 2017 - 1:51:38 PM


Distributed under a Creative Commons Attribution - NonCommercial - NoDerivatives 4.0 International License


  • HAL Id : dumas-01470121, version 1


Geoffroy Canlorbe. Complications vasculo-placentaires chez les femmes enceintes infectées par le VIH : une étude cas-témoin. Médecine humaine et pathologie. 2012. ⟨dumas-01470121⟩



Record views


Files downloads