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Master Thesis

Étude de la qualité de vie des enfants atteints de maladie de Crohn en France

Abstract : Background and aim: Crohn disease presents a range of physical, social and psychological challenges, and can affect the quality of life of those who are affected by it. There is no data about quality of life of children with Crohn disease in France. The present study aims to investigate the health related quality of life (HRQOL) of children having a Crohn disease in France. Methods: children were between 10 and 17 years old, an evolving disease since 6 months, and having a consultation between 1th september and 15 december 2016. Data collected concerned patient and disease characteristics and health related quality of life scored with questionnaire IMPACT III validated in French language. Results: a total of 218 children with Crohn disease were including across 25 hospitals. Median age was 15 years old. Using spearman rank correlation analysis, significant findings included a negative correlation between age and quality of life (r=-0.17; p= 0.009). HRQOL was found to be significantly lower for patients with active disease (according to wPCDAI score) (p<0.0001) and patients with biological inflammatory profile (p=0.02). Conclusion: children with active Crohn disease are more likely to have a lower quality of life. Because there is limited information HRQOL for young patients with Crohn disease in France, the results of the present study may be used as baseline data for future studies
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Master Thesis
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Contributor : Bu Carreire Université de Bordeaux <>
Submitted on : Friday, April 28, 2017 - 11:58:13 AM
Last modification on : Wednesday, August 23, 2017 - 4:41:51 PM
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  • HAL Id : dumas-01515928, version 1



Anne Gourdonneau. Étude de la qualité de vie des enfants atteints de maladie de Crohn en France. Médecine humaine et pathologie. 2017. ⟨dumas-01515928⟩



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