Incidence et facteurs de risque des pneumopathies acquises sous ventilation mécanique en réanimation néonatale

Abstract : Objective: the ventilator associated pneumonia (VAP) is defined as a lung infection occurs in patients receiving invasive or noninvasive mechanical ventilation for more than 48 hours. The main objective of our study was to evaluate the incidence of VAP in NICU, evaluate mortality and associated morbidity and find potential risk factors. Materials and methods: this is a prospective, observational, single-center conducted in NICU in the hospital Armand Trousseau from 01/11/2014 to 10/31/15. All infants aged 28 days or less hospitalized in the ward are included. Results: 381 patients were enrolled including 327 intubated patients. 17 VAP were found an incidence rate of 8.78 VAP / 1000 days of invasive ventilation. VAP occurs on average after 15 days of invasive ventilation. The occurrence of VAP was significantly associated with higher mortality and increased duration of invasive ventilation and noninvasive and length of stay. Newborn whose birth weight is 1000 grams seems to be a population at risk in multivariate analysis but not the term. The presence of a balloon is a risk factor in multivariate analysis and patients who developed VAP have Snappe II score significantly higher in univariate analysis. Conclusion: the VAP in NICU are responsible for an increased mortality and morbidity. Premature newborn less than 1000 grams seem prone to this complication.
Complete list of metadatas

Cited literature [42 references]  Display  Hide  Download

https://dumas.ccsd.cnrs.fr/dumas-01615444
Contributor : Université Paris Descartes - Scd <>
Submitted on : Thursday, October 12, 2017 - 1:50:23 PM
Last modification on : Friday, May 10, 2019 - 10:08:15 AM

File

ThExe_GESLAIN_Guillaume_DUMAS....
Files produced by the author(s)

Identifiers

  • HAL Id : dumas-01615444, version 1

Citation

Guillaume Geslain. Incidence et facteurs de risque des pneumopathies acquises sous ventilation mécanique en réanimation néonatale. Médecine humaine et pathologie. 2016. ⟨dumas-01615444⟩

Share

Metrics

Record views

40

Files downloads

215