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Master Thesis

Non-conformité des prescriptions d’antibiotiques avec les recommandations scientifiques en médecine générale : focus sur l’utilisation des fluoroquinolones et les prescriptions de plus de sept jours

Abstract : Introduction: 70% of antibiotics used in France are prescribed by general practitioners. The identification of these prescription’s determining factors represents a first stage for improvement campaigns on antibiotic use. Objective: This study aims at evaluating in general practice: on one hand, Fluoroquinolone usage modalities, on the other hand, the compliance to a preexisting scientific recommendation, of antibiotic prescription whose duration is more than seven days. Material and Methods: This is an epidemiologic study, multicentric, observational and prospective. Prescription’s inclusion was based upon a draw of 18 pharmacies in Haute-Savoie, spanning over two periods of one week, in January and Mai 2017. Prescribing general practioners where then contacting by phone, and questioned to assess prescribing’s compliance with regards to indication, duration, molecules and dosages. Results: 97 prescriptions were included, among the 40 prescribing Fluoroquinolones, 40.5 % were deemed non compliant. Among the 82 including an antibiotic prescription for more than seven days, 76.8 % were non compliant. Conclusion: The rate of antibiotic prescription, in general practice, not meeting official guidance is high. Policies to rationalise usage remain to be pursued to fight antibioresistance.
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Master Thesis
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https://dumas.ccsd.cnrs.fr/dumas-01617399
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Submitted on : Monday, October 16, 2017 - 3:15:57 PM
Last modification on : Wednesday, July 15, 2020 - 8:58:04 AM
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  • HAL Id : dumas-01617399, version 1

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Amélie Jegoux, Cécile Hericher. Non-conformité des prescriptions d’antibiotiques avec les recommandations scientifiques en médecine générale : focus sur l’utilisation des fluoroquinolones et les prescriptions de plus de sept jours. Médecine humaine et pathologie. 2017. ⟨dumas-01617399⟩

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