Délais de prise en charge et survie des patients atteints de tumeurs des voies aérodigestives supérieures : étude sur la population guadeloupéenne entre 2008 et 2016

Abstract : BACKGROUND In Guadeloupe, cancers are the 2nd cause of death; among diagnosed cancers, head and neck localization rank in 4th place. Care delays goes from the first time seeing and ENT doctor to the 1st treatment. The aim of this study is to analyze delays' evolution and its impact on survival. METHODS We did a retrospective study between 2008 and 2016 on patients with head and neck cancer in Guadeloupe. We collected epidemiological and histological datas, TNM stage, treatment type, and delays between 1st consultation, anatomopathological diagnosis, care-decision and beginning of treatment. RESULTS 500 patients were included, most of localization were Lips-Mouth-Pharynx, most were at T3- T4 stage and 94% presented squamous cell carcinoma. The standardized rate of head and neck tumors was lower than that reported in France. Between 2008 and 2016 we discovered that delays between 1st ENT consultation and diagnosis were under 10 days, then, were between 12 and 19 days until collegial care final decision and less than 40 days until the start of the treatment. The reported delays didn’t have any impact on survival over 3 years, however, we observed a better survival rate for patients diagnosed with a T1-T2N0 TNM stage and who under went surgical care. CONCLUSION Reported delays in Guadeloupe are sufficient and coherent with up to date recommendations and articles' datas, more over they had no negative impact on survival rate for patient with head and neck cancer.
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Master Thesis
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Gunther Aubin Huyghues Des Étages. Délais de prise en charge et survie des patients atteints de tumeurs des voies aérodigestives supérieures : étude sur la population guadeloupéenne entre 2008 et 2016. Organes des sens. 2018. ⟨dumas-01985245⟩

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