Caractéristiques et devenir des patients sous triple thérapie antithrombotique pour fibrillation/flutter auriculaire et coronaropathie stentée au CHU de Bordeaux de 2010 à 2016

Abstract : Introduction: atrial fibrillation and coronary artery disease with stent implantation are real public health problems. Association of these diseases is associated with high thromboembolic risk. So, a triple antithrombotic therapy (anticoagulation and dual antiplatelet therapy) is usually used. Aim. Our aim was to estimate prevalence of bleeding and thromboembolic events, cardiovascular and all-cause mortality in a population under triple therapy due to these conditions. Material and Methods: we did an observational, retrospective study concerning patients admitted to cardiological hospital of Haut-Lévêque at university hospital of Bordeaux, between October 1st, 2010 and November 30, 2016, for atrial fibrillation and coronary artery disease with stent implantation. Results: among 446 hospitalizations concerning 425 patients under triple antithrombotic therapy, we noticed 16.3% of BARC≥2 bleeding, 0.9% of acute coronary syndromes, 1.1% of strokes, 1.79% of cardiovascular deaths and 1.12% of all-cause deaths. Conclusion: patients under triple antithrombotic therapy are fraily and at high risk of thrombotic and bleeding events. Several improving directions emerge from our study to minimize bleeding risk and optimize triple therpay patients management.
Document type :
Master Thesis
Complete list of metadatas

Cited literature [127 references]  Display  Hide  Download

https://dumas.ccsd.cnrs.fr/dumas-02124725
Contributor : Bu Carreire Université de Bordeaux <>
Submitted on : Thursday, May 9, 2019 - 6:30:16 PM
Last modification on : Saturday, June 29, 2019 - 1:25:10 AM

File

Med_generale_2019_Pierrard.pdf
Files produced by the author(s)

Identifiers

  • HAL Id : dumas-02124725, version 1

Collections

Citation

Elisa Pierrard. Caractéristiques et devenir des patients sous triple thérapie antithrombotique pour fibrillation/flutter auriculaire et coronaropathie stentée au CHU de Bordeaux de 2010 à 2016. Médecine humaine et pathologie. 2019. ⟨dumas-02124725⟩

Share

Metrics

Record views

13

Files downloads

95