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Master Thesis

Incidence de la iatrogénie sur les motifs de recours aux urgences

Abstract : Introduction: Iatrogeny or any unwanted consequence of any medical act is a public health problem in our society. In the 2000s, adverse drugs reactions (ADRs) are responsible for 14.7% of emergency room admissions and 3.6% of hospitalizations. The purpose of our study intends to evaluate the incidence of ADRs among all the purposes of emergency consultations. Method: This study is a retrospective one which analyses records of patients admitted to the emergency department of Toulon’s hospital center during the summer of 2018. A cross-analysis of the reason for emergency visits and the patient’s treatments allowed us to reveal the iatrogenic cases. Results: A total of 2279 cases were gathered. The ADRs are responsible for 288 emergency admissions (12.46%). Regarding the 432 hospitalizations, 109 were induced by an ADR, i.e. a quarter of all hospitalizations. Multivariate analysis revealed that an age above 65 years (OR 7.71 [5.13-11.69]) and polypharmacy (OR 11.70 [6.57-20.47]) are significant risk factors of ADRs. The drug class most involved was psychoactive drugs (43.57%) Conclusion: Our results are consistent with data published from the literature. The assessment of the benefit / risk ratio is needed before any medical prescription because a prescription could cause adverse drug events, especially towards the elderly, a frail and overmedicated population. The General Practitioner plays a crucial role in the prevention of ADRs because he is at the core of the care pathway.
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Submitted on : Wednesday, December 4, 2019 - 11:43:32 AM
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  • HAL Id : dumas-02393154, version 1



Guillaume Bosco. Incidence de la iatrogénie sur les motifs de recours aux urgences. Sciences du Vivant [q-bio]. 2019. ⟨dumas-02393154⟩



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