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Master Thesis

Quelques considérations sur Boerhavia diffusa L., espèce médicinale aux Antilles introduite dans la pharmacopée française

Abstract : Boerhavia diffusa is a pantropical perennial plant belonging to the Nyctaginaceae family. It is a major plant in Ayurvedic and Unani medicine, known in Martinique and Guadeloupe as Patagon rouge (wouj in Creole) or Patagon Valeriane. Already present in the Indian and Brazilian pharmacopoeias, it was registered in 2013 with the French Pharmacopoeia to promote overseas biodiversity and for its traditional use as a treatment for sore throats in Martinique. The objective of this work is to assess the knowledge on botany, phytochemical composition, pharmacological properties, ethnopharmacological data of this plant and to determine if it has a potential in phytotherapy or for the pharmaceutical industry. An alkaloid, phenolic compounds (rotenoids, flavonoids, lignans), steroids, triterpenoids, xanthones were found. Many pharmacological activities have been demonstrated (antioxidant, anti-inflammatory, antinociceptive, antifibrinolytic, hepatoprotective, renal, cardiac, antiasthmatic, spasmolytic, antimicrobial, antidiabetic, anticancer) and allow to validate some of its traditional uses. This plant is used in cosmetology by several laboratories as in India, drugs contain it in their formulations. Some molecules isolated from Boerhavia diffusa, such as punarnavine, boervinones B, H, uridine triacetate, quercetin 3-O-α-D-rhamnoside, have shown good results in infectiology or oncology.
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Master Thesis
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https://dumas.ccsd.cnrs.fr/dumas-02432544
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Submitted on : Wednesday, January 8, 2020 - 2:53:14 PM
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Guilhem Jacques-Gustave. Quelques considérations sur Boerhavia diffusa L., espèce médicinale aux Antilles introduite dans la pharmacopée française. Sciences du Vivant [q-bio]. 2019. ⟨dumas-02432544⟩

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