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Master Thesis

Diagnostic et suivi de la bilharziose urinaire chez de jeunes migrants arrivés récemment en France

Abstract : Context: Urinary bilharzia affects 90 million people worldwide and is caught by bathing in S. Haematobium infested waters in sub-Saharan Africa. Every year 25 000 sub-Saharan Africans migrate to France. Objective: to analyse the diagnosis and impact of treatment on young migrants suffering from urinary bilharzia. Method: setting up follow up appointments and collecting sociodemographic, clinical, biological and ultrasound data from patients who were diagnosed and treated at the Guy Môquet unit of the Hôtel Dieu between Jan. 2011 and Sept. 2016. Results: 48 West African males – diagnosed a median 7 months after arriving in France – were surveyed. 91% presented symptoms (86% had hematuria, 43% dysuria, 31% mictional burns). 70% had hypereosinophilia of 0.86 g/l on average and between 0.5 and 1.54 g/l in 90% of cases. 62% of ultrasounds carried out presented bladder wall thickening of which 12% had additional lesions. 60% of patients were prescribed one course of praziquantel, and 33% were prescribed two. 22 patients attended their follow up: 90% were asymptomatic, 86% had negative urine dipstick test results, 15% had persistent bladder thickening. 23% were not cured by their first course of drugs either due to a failure to follow treatment instructions, too low a dose or a false positive due to early testing. 32% could not remember their diagnosis and 55% were uninformed about bilharzia. Only one patient had notified their GP. Conclusion: this study highlights the importance of rigorous interviews and urine dipstick testing in screening for and monitoring bilharzia. For this specific population we recommend that the drug be administered by a medic in one single dose of 40 mg/kg.
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Master Thesis
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  • HAL Id : dumas-02486169, version 1

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Marie-Astrid Naccache. Diagnostic et suivi de la bilharziose urinaire chez de jeunes migrants arrivés récemment en France. Médecine humaine et pathologie. 2018. ⟨dumas-02486169⟩

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