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Master Thesis

Fasciolose humaine à Fasciola gigantica contractée au Burkina Faso. Le point sur la fasciolose humaine en France au début du XXIe siècle

Abstract : Introduction : fasciola gigantica fascioliasis are rare, present only in tropical areas. Further to the observation in Nice of a human F. gigantica fascioliasis caught in Burkina Faso, we ask us about the current situation in France. France is known to be an endemic area of fascioliasis. Around 300 cases each year are estimated. We think that this data is not updated. However fascioliasis seems to have been less diagnosed recent decades. This study aims to evaluate the incidence of human fascioliasis in France and establish the epidemiological profile.
Patients and methods : An epidemiological descriptive retrospective multicentric study has been realized with laboratory of parasitology-mycology of university hospitals of France. The laboratory Eurofins participated too. The first criteria was every fascioliasis diagnosis by serology or coprology from 2009 to 2018. A questionnaire has been spread to each diagnosis in order to collect additional clinical and epidemiological informations. A retrospective descriptive analysis has been realized.
Results : with a participation rate of 63%, we collect finally 33 cases diagnosed in a period of 10 years, from 2009 to 2018 in France. We can estimate an average number of cases each year and a rate incidence of 0,005 cases for 100000 people. Ile-de-France, Auvergne-Rhône-Alpes, Occitanie and Bourgogne-Franche-Comté represent 64% of cases. Regarding the place of contamination of cases, 9 are imported (27%), 2 autochthonous (6%) and 22 (67%) without any information about the origin. Regarding the diagnsosis, it is mainly an immunological diagnosis : 31 serological diagnosis (93,9%) and 2 coprological examination (6,1%).
Conclusion: human fascioliasis is rare in France and has nearly disappeared of the land since the beginning of the twenty first century. Only isolated and sporadic cases remain.
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Master Thesis
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Submitted on : Monday, June 15, 2020 - 4:28:37 PM
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Laurencie Massamba. Fasciolose humaine à Fasciola gigantica contractée au Burkina Faso. Le point sur la fasciolose humaine en France au début du XXIe siècle. Médecine humaine et pathologie. 2020. ⟨dumas-02868867⟩

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