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Master Thesis

Étude Hypno-Séno : anesthésie générale versus hypno-tumescence en chirurgie mammaire conservatrice : évaluation de la qualité des marges de résection chirurgicale

Abstract : Hypnosis is often proposed to patients in the comprehensive care of breast cancer. Many studies have evaluated the benefit of a preoperative hypnosis session. There is a lack of literature evaluating the performance of breast surgery under local anaesthesia associated with hypnosis. Since July 2017 the Grenoble-Alpes University Hospital Center (CHUGA) performs conservative breast surgery under hypno-tumescence. The operation is performed under hypnosis and local anesthesia by injecting 100 to 1000 ml of lidocaine into the surgical area. This technique can modify the anatomical positions and make surgery more difficult. The main outcome of our study is to show that the carcinological quality of surgical management under hypno-tumescence and sedation is no different from standard management under general anaesthesia. Material and method: After approval by the hospital's ethics committee, protocol MR-004, we conducted a retrospective study, at the CHUGA, from July 2017 to December 2019, comparing the number of surgical re-excision for positive margins of conservative breast surgeries performed under hypnosis to those performed under general anesthesia. To improve comparability between groups, patients were matched by a propensity score. Results: The number of re-excision in the hypno-tumescence group was 7/38 (9.2%) patients and 7/38 (9.2%) patients in the general anesthesia group. There was no statistically significant difference. The overall re-excision rate is 18.4%. Discussion: Our study is the first to evaluate the quality of carcinological resection under hypno-tumescence compared to standard management and shows that there is no significant difference between the two groups.
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Master Thesis
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https://dumas.ccsd.cnrs.fr/dumas-02877811
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Submitted on : Monday, June 22, 2020 - 4:53:23 PM
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Anne-Pauline Cungi. Étude Hypno-Séno : anesthésie générale versus hypno-tumescence en chirurgie mammaire conservatrice : évaluation de la qualité des marges de résection chirurgicale. Médecine humaine et pathologie. 2020. ⟨dumas-02877811⟩

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