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Master Thesis

Place des mélanges d'acides aminés dans la prise en charge thérapeutique de l'allergie aux protéines de lait de vache par les pédiatres de Basse-Normandie

Abstract : Introduction. Cow's milk protein allergy (CMPA) is the earliest-presenting and most common food allergy in children. For infants presenting with CMPA that are not breast-fed, there are two types of formula available: Extensively Hydrolysed formula (eHF) and Amino Acid-based Formula (AAF). Guidelines for AAF prescription are sometimes unclear and contradictory from one country to another. The main objective of our study was to assess AAF prescription practice from paediatricians in Lower Normandy in the treatment of CMPA. Material & Methods. It was a transversal multicenter observational study. A questionnaire was sent to all paediatricians working in Lower Normandy, regardless of practice type, either by electronic or postal means. The percentage of correct answers for each question was calculated. A score from 0 to 9 was assigned to each participant. Results. The questionnaire was sent to a total of 134 paediatricians, of which 45 answered. The average score obtained was 3.1/9. None of the participants ticked the three correct indications for first-line AAF prescription. 22.2% prescribe AAF when severe symptoms are combined with failure to thrive. However, 86 % of them prescribe AAF in second line after failure of eHF at 4 weeks in accordance with most guidelines. Conclusion. Our findings suggest that the indications of AAF are not well known. Writing French guidelines could improve knowledge among paediatricians and general practitioners.
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Master Thesis
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https://dumas.ccsd.cnrs.fr/dumas-02932217
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Submitted on : Monday, September 7, 2020 - 3:48:31 PM
Last modification on : Wednesday, October 14, 2020 - 4:01:37 AM

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  • HAL Id : dumas-02932217, version 1

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Océane Briand. Place des mélanges d'acides aminés dans la prise en charge thérapeutique de l'allergie aux protéines de lait de vache par les pédiatres de Basse-Normandie. Médecine humaine et pathologie. 2020. ⟨dumas-02932217⟩

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