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Master Thesis

Perforation intestinale chez les patients transplantés hépatiques au CHU de Montpellier : étude rétrospective observationnelle

Abstract : Liver transplantation enhances the prognosis of patients with cirrhosis or hepatocellular carcinoma. However, some patients develop complications among which intestinal perforation for which the prognosis is poor.The aim of this study is to evaluate the characteristics of patients who developed an intestinal perforation so as to identify possible risk factors. Another objective is to describe the type of surgery done and its impact on survival. METHODS: an observational retrospective study was conducted in the Universitary Hospital of Montpellier between 2010 and 2019 as well as an international survey.The study analysed the different parameters of patients presenting a perforation and the type of surgical treatment along with the presence or absence of reoperation. RESULTS: 20 patients out of 617 developed a perforation. Mortality rate was 75%. Patients who had a conservative treatment presented more reoperations than those who had a radical treatment. Mortality related to perforations was 33% in the conservative treatment group compared to 0% in the other.The survey showed that conservative treatment was privileged in case of gastric and duodenal perforation and radical treatment was privileged in cas of ileal or colic perforation. CONCLUSION: intestinal perforation in the liver transplant patient has a high mortality. A radical treatment should be considered in case of perforation.
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Master Thesis
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Contributor : Scd Université de Montpellier <>
Submitted on : Friday, October 16, 2020 - 2:21:22 PM
Last modification on : Monday, February 15, 2021 - 3:22:24 AM


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  • HAL Id : dumas-02969198, version 1


Bader Al Taweel. Perforation intestinale chez les patients transplantés hépatiques au CHU de Montpellier : étude rétrospective observationnelle. Médecine humaine et pathologie. 2019. ⟨dumas-02969198⟩



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