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Master Thesis

Chirurgie pour maladie de Crohn pendant la grossesse : une enquête nationale

Abstract : Background and aims: Crohn's disease frequently affects young women and may require surgery during pregnancy. Data regarding operation for Crohn's disease in expectant mothers are scare. Materials and methods: This was a retrospective nationwide survey from the GETAID Chirurgie. Any woman with Crohn's disease undergoing surgery during pregnancy was eligible. Results: A total of 15 cases were collected between 1992 and 2019. Most operations were performed due to penetrating or stricturing complications. Mean gestational age at delivery was 34 weeks, with a mean birth weight of 2507 g. Maternal post-operative complications occurred in two-thirds of cases. Maternal mortality rate was 6.7% and neonatal mortality rate 9.1%. Conclusions: This is the largest case series of surgery for Crohn's disease during pregnancy. This operation may have significant morbidity and mortality for mother, fetus, and newborn. Indication needs to be tailored to maternal status, disease severity, and gestational age. Surgery should be managed by experienced gynecologists, physicians, and surgeons. Active Crohn's disease may be associated with a greater risk to the fetus than the surgical procedure itself.
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Master Thesis
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Submitted on : Thursday, October 22, 2020 - 10:51:53 AM
Last modification on : Tuesday, November 24, 2020 - 4:00:15 PM
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  • HAL Id : dumas-02974211, version 1


Thomas Chateau. Chirurgie pour maladie de Crohn pendant la grossesse : une enquête nationale. Médecine humaine et pathologie. 2020. ⟨dumas-02974211⟩



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