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Master Thesis

Impact de la réadaptation cardiaque sur la fonction diastolique et les capacités fonctionnelles

Abstract : Background: Cardiac Rehabilitation (CR) can reduce mortality and prevent Cardiovascular Diseases (CVD) recurrence, but published data do not indicate an improvement in systolic function. However, there still has not been much research into the relationship between diastolic function and functional capacity during CR.
Objectives: assess the evolution of clinical data and echocardiographic measurements including diastolic function and to objectively assess physical capacity before and after 20 sessions of CR
Methods: prospective, cross-sectional study in the Bastia CR department from December 2018, to July 2019. All patients with an indication for CR and a left ventricle ejection fraction (LVEF)  50% were invited to participate in the study.
The assessment on inclusion and after CR included clinic measurements, the INTERHEART score and the maximum effort load (Wattmax). Using echocardiography, we measured the LVEF, the Tei index, and the tricuspid annular plane systolic excursion (TAPSE), septal and lateral E/e’ ratio and the isovolumetric relaxation time (IVRT).
Results: RC allowed a significant decrease in weight (-1kg with p=0.004), abdominal perimeter (-1.3cm with p<0.0001) and the INTERHEART risk score (-2.7 points with p<0.0001). Maximum physical effort capacities also were increased by 27% (p<0.0001). These improvements are correlated with significant variations in Tei index (p=0.009), TAPSE (p=0.004), septal E/e’ ratio (p=0.04) and the IVRT (p<0.0001). These elements are prognostic markers of morbidity, mortality and quality of life. Thus the benefit shown by the CR program is evidenced from both an echographic, an ergometric and a clinical point of view.
Document type :
Master Thesis
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Contributor : Bibliothèque Universitaire de Médecine Nice <>
Submitted on : Tuesday, October 27, 2020 - 5:52:14 PM
Last modification on : Friday, February 26, 2021 - 3:10:56 AM


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  • HAL Id : dumas-02981038, version 1


Thanh-Danh Ly. Impact de la réadaptation cardiaque sur la fonction diastolique et les capacités fonctionnelles. Médecine humaine et pathologie. 2019. ⟨dumas-02981038⟩