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Master Thesis

État des lieux de la corticothérapie anténatale chez les prématurés : étude épidémiologique rétrospective comparative au CHUGA

Abstract : Objectives: The main objective of this study is to evaluate the prevalence of antenatal corticosteroid therapy (used in the prevention of morbidity and mortality in children born prematurely) in the three main classes of premature babies. Materials and methods: This is a retrospective monocentric comparative study. The data will be collected by consulting the computerized medical records of all the hospitalized children in the neonatology department of CHUGA, those born between 30/06/2017 and 30/06/18 included. Results: In our study population, the rate of antenatal corticosteroid therapy (at least one full course of treatment that is to say two injections of corticosteroids) is 63.3% on extreme prematures born between 24 and 27 + 6 weeks of gestation. This rate increases to 75.2% in very premature babies born between 28 and 31 + 6 weeks. Then, it decreases in the class of average premature babies born between 32 and 33 + 6 weeks with an antenatal corticosteroid rate at 69.5%. Conclusion: The 190 premature newborns benefited in at least 71,6% oh the cases from a complete corticosteroid treatment (136 infants). In addition, despite the latest national recommendations in 2016 not to repeat corticosteroid treatments, this practice is still widespread in obstetrics departments.
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https://dumas.ccsd.cnrs.fr/dumas-03048733
Contributor : Jean-Hugues Morneau <>
Submitted on : Wednesday, December 9, 2020 - 3:03:26 PM
Last modification on : Saturday, December 12, 2020 - 3:26:08 AM

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  • HAL Id : dumas-03048733, version 1

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Sophie Mermet. État des lieux de la corticothérapie anténatale chez les prématurés : étude épidémiologique rétrospective comparative au CHUGA. Gynécologie et obstétrique. 2020. ⟨dumas-03048733⟩

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