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Master Thesis

Quick-Wee versus stimulation vésicale pour recueillir des urines de second jet chez le nourrisson non continent : un essai randomisé contrôlé

Abstract : Introduction: Urinary tract infections are common, in around 1 to 4% in boys and 3 to 8% in girls under 2 years old. The diagnosis is difficult because of nonspecific symptoms and the risk of urine analysis contamination, according to the sampling methods in pre-continent infants. The urethral catheterization and suprapubic puncture are recommended by the American Academy of Pediatrics, because of a low contamination rate but this technique is invasive. While the National Institute for Health and Care Excellence preconize clean catch urine for its minor invasiveness and its acceptable contamination rate but is difficult in pre continent infants. Recently, two methods have been described: Quick-Wee method by Kaufman et al (suprapubic stimulation with cold saline-soaked gauze) and the bladder stimulation by Herreros et al then by Tran et al (pubic tapping alternating with lumbar massages). This trial aim to compare the effectiveness in collecting midstream urine by bladder stimulation versus the Quick-Wee method, in infants under 1 year, before walking.
Methods and analysis: This study is a randomized controlled trial of 230 infants under 1 year and before walking, who need a urine analysis, conducted in 4 Pediatrics Emergencies Departments in France. Patients will be randomized into two groups: bladder stimulation and Quick-wee method. The primary endpoint will be the success rate of voiding in less than 5 minutes (at least 2 mL of urines). Secondary outcomes measure the delay of collecting, the comfort, the quality of urines and the risk factors associated with the failure of the two techniques.
Ethics and dissemination: The study protocol was approved by the French national ethic committee (consultative committee of the protection of persons) and is registered with the Clinical Trials Registry – NCT04587999. The results of the study will be published in a peer-reviewed journal. Protocol version identifier: version 1.
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Master Thesis
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Submitted on : Thursday, January 14, 2021 - 4:02:34 PM
Last modification on : Tuesday, July 13, 2021 - 3:24:00 AM


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  • HAL Id : dumas-03110459, version 1


Jade Janicot. Quick-Wee versus stimulation vésicale pour recueillir des urines de second jet chez le nourrisson non continent : un essai randomisé contrôlé. Médecine humaine et pathologie. 2020. ⟨dumas-03110459⟩



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