Skip to Main content Skip to Navigation
Master Thesis

Colonisation fécale par des entérobactéries productrices de bêta-lactamases à spectre étendu chez les individus sains dans la communauté : actualisation d’une revue de littérature de 2016

Abstract : Introduction: antibioresistance is one of the biggest threat of the twenty first century. The fecal carriage of extended spectrum beta lactamase producing enterobacteria (ESBL-PE) is a hidden plague and the world prevalence was 14% in 2016, according to Karanika and al. systematic review of the litterature. The goal of our study was to determine in which direction this rate had evolved. Methods: systematic review of the litterature acording to the PRISMA model via the PUBMED and SCOPUS databases and among the grey litterature between july 15th 2015 and may 20th 2020. Selection of the studies containing data regarding the fecal carriage of ESBL-PE among healthy individuals of the community for each World Health Organization defined region. The prevalence of ESBL-PE and the distribution of the different types of bacteria and enzymes were extracted. Results: twelve studies out of 1014 were included. The pool prevalence of ESBL-PE fecal colonization is currently estimated at 22,9% worldwide versus 14% in 2016, showing an 8,9% growth since july 2015. The highest prevalence is in South East Asia (41,6%) and in Africa (38%) and the smallest in the West Pacific region (15,4%) and in Europe (6,1%). No study corresponding to the inclusion criteria was found for the American and East Mediterranean regions. The most frequently isolated bacteria is Escherichia coli and the enzymes are CTX-M 14 and 15. Conclusions: the prevalence of ESBL-PE fecal carriage among healthy individuals in the community, altough uneven, globally keeps on growing. It is becoming worrysome and must be taken in consideration by the industrials, the politicians, the health workers and the population in order to avoid a heath disaster.
Document type :
Master Thesis
Complete list of metadatas

https://dumas.ccsd.cnrs.fr/dumas-03116876
Contributor : Bu Carreire Université de Bordeaux <>
Submitted on : Wednesday, January 20, 2021 - 4:35:41 PM
Last modification on : Friday, January 22, 2021 - 3:11:37 AM

File

Med_generale_2020_Peyraud_Vall...
Files produced by the author(s)

Identifiers

  • HAL Id : dumas-03116876, version 1

Collections

Citation

Caroline Peyraud, Fanny Vallet. Colonisation fécale par des entérobactéries productrices de bêta-lactamases à spectre étendu chez les individus sains dans la communauté : actualisation d’une revue de littérature de 2016. Médecine humaine et pathologie. 2020. ⟨dumas-03116876⟩

Share

Metrics

Record views

20

Files downloads

22