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Master Thesis

Évaluation du dépistage cytologique des cancers du col de l’utérus dans les Alpes Maritimes : étude rétrospective sur la période 2016 – 2018 par exploitation de la base CRISAP

Abstract : Introduction: 2920 new cases of cervical cancer (CC) were diagnosed in France in 2018. Our study focused on invasive CC cases diagnosed in the Alpes-Maritimes (AM) from January 1, 2016 to December 31, 2018. Our goals were to determine: the number of CC cases, histological types, and the concerned population; the weaknesses of the screening that could explain CC development.
Material and Methods: the history of PAP test screening during 4 years before the CC diagnosis was collected in all the laboratories of Anatomy and Cytology Pathology of the AM, accredited ISO 15189 standard for CC cytology.
Results: 148 patients aged 26-95 years developed invasive CC between 2016 and 2018. The screening weaknesses related: to the PAP test sensitivity: 39% of screened patients (33/85); lack of screening : 34% of patients of screening- age women (33/96); pathological PAP tests time management: 18% of patients (14/76); screening age exit : 35% of patients over 65 years of age (52/148)
Discussion: human papillomavirus (HPV) testing in primary screening (women aged 30-65 years) will improve screening. Other weaknesses may potentially persist despite organized CC screening, particularly for women over 65 years who are "excluded" from the organized screening. These women should be made aware of the need for regular gynecological follow-up and consideration should be given to stopping screening at age 65.
This study was carried out thanks to the CRISAP Alpes Maritimes and the Public Health Department (CHU of Nice).
Document type :
Master Thesis
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https://dumas.ccsd.cnrs.fr/dumas-03343026
Contributor : Bibliothèque Universitaire de Médecine Nice Connect in order to contact the contributor
Submitted on : Monday, September 13, 2021 - 5:38:25 PM
Last modification on : Tuesday, December 7, 2021 - 4:10:58 PM

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  • HAL Id : dumas-03343026, version 1

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Lydie Cohen. Évaluation du dépistage cytologique des cancers du col de l’utérus dans les Alpes Maritimes : étude rétrospective sur la période 2016 – 2018 par exploitation de la base CRISAP. Médecine humaine et pathologie. 2021. ⟨dumas-03343026⟩

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