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Master Thesis

NEURODATA : devenir à 12 mois et facteurs pronostiques des hémorragies sous-arachnoïdiennes par rupture d’anévrisme prises en charge au CHU de Caen entre novembre 2015 et décembre 2019

Abstract : Objective: The follow-up of patients after aneurysmal Subarachnoid Hemorrhage (SAH) is poorly documented beyond 6 months. The aim of this study was to assess the functional outcome at 12 months of these patients. Study design: This is a monocentric prospective observational study. Material and method: Adults patients with SAH treated between November 2015 and December 2019 in a French university hospital were included. Evaluation was performed at 3, 6 and 12 months. Primary endpoint was poor functional outcome at 12 months defined by modified Rankin Scale [3-6]. Results: The study population included 198 patients whom 9 were lost to follow-up. A poor functional outcome at 12 months concerned 77 patients (41%). The associated factors in multivariate analysis were: recurrent bleeding (OR 5.40 [1.92; 15.1]); WFNS grade [3-5] (OR 4.72 [1.80; 12.3], cardiovascular risk factors ≥ 2 (OR 4.12 [1.61; 10.5]), external ventricular drainage (OR 3.88 [1.42; 10.6]), endovascular treatment of the aneurysm (OR 0.330 [0.127; 0.857]). Neurocognitive disorders were reported by 62 patients (45%). Fifty-four patients (56% of the working population before the event) were able to resume their professional activity. Conclusion: Morbidity remains high at 12 months despite an improvement during the follow-up of the neurological prognosis and neurocognitive disorders.
Document type :
Master Thesis
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https://dumas.ccsd.cnrs.fr/dumas-03378965
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Submitted on : Thursday, October 14, 2021 - 5:48:36 PM
Last modification on : Thursday, October 21, 2021 - 5:02:32 AM
Long-term archiving on: : Saturday, January 15, 2022 - 7:56:43 PM

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  • HAL Id : dumas-03378965, version 1

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Loïc Plattier. NEURODATA : devenir à 12 mois et facteurs pronostiques des hémorragies sous-arachnoïdiennes par rupture d’anévrisme prises en charge au CHU de Caen entre novembre 2015 et décembre 2019. Médecine humaine et pathologie. 2021. ⟨dumas-03378965⟩

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