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Master Thesis

Bacillus cereus invasive infections in preterm neonates : an up-to-date review of the litetature

Abstract : Bacillus cereus group comprises eighteen validated species that are a widespread, Gram-positive, spore-forming environmental bacterium. B. cereus sensu stricto is the third most common cause of food poisoning in Europe. In high-risk individuals, such as preterm neonates, B. cereus infections can cause fatal infections. It is important to note that the phenotypic identification methods commonly used in clinical microbiology laboratories do not distinguish B. cereus sensu stricto and the other members of the group (excluded B. anthracis). As a result, all the invasive infections attributed to B. cereus are not necessarily due to B. cereus sensu stricto but likely to others closely related species of B. cereus group. Next-generation sequencing (NGS) should be used to confirm if the strains involved in previously reported B. cereus invasive infections preferentially belong to formerly known or emerging individual species. Moreover, infections related to B. cereus group species have probably been overlooked since its isolation in human bacteriological samples had for a long time been regarded as a contaminant. Recent studies have questioned the emergence or re-emergence of B. cereus invasive infections in preterm infants. This review reports our current understanding of B. cereus infections in neonates, including taxonomical updates, microbiological characteristics, bacterial identification, clinical features, host-pathogen interactions, environmental source of contamination and antimicrobial resistance.
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Master Thesis
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Contributor : Bibliothèque Universitaire de Médecine Nice Connect in order to contact the contributor
Submitted on : Thursday, December 2, 2021 - 3:19:31 PM
Last modification on : Saturday, March 19, 2022 - 3:15:57 AM


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  • HAL Id : dumas-03463596, version 1


Alicia Chevalier. Bacillus cereus invasive infections in preterm neonates : an up-to-date review of the litetature. Human health and pathology. 2021. ⟨dumas-03463596⟩



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