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Master Thesis

Recours à la splénectomie diagnostique : caractéristiques de 20 patients et étiologies identifiées sur le CHU Bicêtre et l’HIA Percy de 2010 à 2019

Abstract : Splenectomy is the surgical removal of the spleen and it can lead to complications.
Splenectomy is indicated in the case of trauma to the spleen, during tumor reduction surgery or even during another abdominal surgery with secondary lesion. These indications are called surgical.
Splenectomy is indicated in haematological diseases, immunological diseases or even in cystic diseases. These indications are said to be medical.
Less frequently splenectomy is performed for diagnostic purposes as part of an unsuccessful prior etiological investigation.
In order to explore the pathologies which led to perform a diagnostic splenectomy, we studied on two hospital centers, the medical files of 142 patients who underwent a splenectomy for all reasons over a 10 years period.
We identified 20 diagnostic splenectomies. Diagnostic splenectomy was mainly performed to explore unexplained splenomegaly for 13 patients and fever of unknown origin since at least 3 weeks for 10 patients. The others patients had the surgery for different causes ( cytopenias, abdominal symptoms , malignant hemopathies relapse suspicion). Splenectomy contributed to the diagnosis in 17 out of 20 cases with a majority of lymphoid hematological malignancies (n=13). The main pathology found is the diffuse large B-cell lymphoma (n=7).
Our study made it possible to identify and characterize the patients for whom a diagnostic splenectomy was performed. We have described the etiological surveys in order to specify the pre-operative investigations carried out during the diagnostic process. This highlighted the importance of the PET scanner.
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Master Thesis
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https://dumas.ccsd.cnrs.fr/dumas-03469619
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Submitted on : Tuesday, December 7, 2021 - 6:29:51 PM
Last modification on : Thursday, April 7, 2022 - 2:28:02 PM

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  • HAL Id : dumas-03469619, version 1

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Jean Maillot. Recours à la splénectomie diagnostique : caractéristiques de 20 patients et étiologies identifiées sur le CHU Bicêtre et l’HIA Percy de 2010 à 2019. Médecine humaine et pathologie. 2020. ⟨dumas-03469619⟩

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