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Master Thesis

Qualité d’image et performances diagnostiques de la séquence 3D de cholangio-pancréatographie IRM avec compressed sensing en imagerie pancréatique

Abstract : Objective: to compare image quality and diagnostic performances in 3D Magnetic Resonance Cholangiopancreatography (3D MRCP) with Compressed Sensing (CS) in free-breathing and in a breath-hold, with standard 3D MRCP in patients with suspected pancreatic diseases at 3T.
Material and methods: with approval from the Committee for the Protection of Persons and after informed consent, 56 consecutive patients (29 men and 27 women; median age 59 years; for 57 MRI realized) were prospectively included. Three protocols were randomly performed: CS in a breath-hold (CS-BH), CS and Standard. The acquisition time was recorded. Quality image parameters (overall image quality, degree of artifacts, background suppression, bilio-pancreatic ducts visualization) and diagnostic performances (anatomical variants, ductal abnormalities, cystic lesions) were evaluated on 5-point scale by two radiologists blinded to the protocols.
Results: acquisition time was 279s, 176s and 22s for Standard, CS and CS-BH, reducing scan time by 37% and 93% with CS. There was no significant difference in overall quality image, degree of artifacts and background suppression between Standard and CS-BH. In CS-BH group there were less non-diagnostic scans (3% in CS-BH versus 19% in Standard and 21% in CS, p<0.05), more satisfying quality scans (78% in CS-BH versus 66% in Standard and 58% in CS, p<0.05) and less severe artifacts (2% in CS versus 18% in Standard and 16% in CS, p<0.05). Middle pancreatic duct was better visualized with CS-BH compared with Standard (p=0.015) or with CS (p<0.001). Diagnostic performances were equal between all three protocols. There were less undeterminate MRI in CS-BH group for both readers.
Conclusion: 3D MRCP with CS is feasible in clinical routine, time-saving, with no degradation in image quality and no reduction of diagnostic performances. 3D MRCP in a BH is recommended at 3T.
Document type :
Master Thesis
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Submitted on : Thursday, March 31, 2022 - 3:24:47 PM
Last modification on : Monday, April 4, 2022 - 3:10:37 AM


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Inès Mannes. Qualité d’image et performances diagnostiques de la séquence 3D de cholangio-pancréatographie IRM avec compressed sensing en imagerie pancréatique. Médecine humaine et pathologie. 2018. ⟨dumas-03626449⟩



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